Summary
Mutations conferring resistance to sulfonylurea herbicides have been identified at two unlinked genetic loci (SuRA and SuRB) in Nicotiana tabacum. A mutation (S4) residing at the SuRB locus causes production of an altered form of acetolactate synthase (ALS) that is insensitive to inhibition by sulfonylurea herbicides and that constitutes approximately 50% of total ALS activity. Another mutation (C3) at the SuRA locus similarly results in herbicide resistance of approximately half of the total ALS activity. These results suggest that N. tabacum possesses at least two isozymic forms of ALS. The relative and absolute amounts of the isozymes are affected by a mutation that segregates independently of C3.
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Communicated by G. Melchers
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Chaleff, R.S., Bascomb, N.F. Genetic and biochemical evidence for multiple forms of acetolactate synthase in Nicotiana tabacum . Mol Gen Genet 210, 33–38 (1987). https://doi.org/10.1007/BF00337755
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DOI: https://doi.org/10.1007/BF00337755