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Cerebrospinal fluid imaging using serial metrizamide CT cisternography

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Summary

Twenty-five patients studied by serial metrizamide (Amipaque) CT cisternography were used to analyze CSF kinetics. Delayed CSF flow patterns were noted in 7 patients, while intermediate patterns occurred in 4. The abnormal cisternogram was characterized primarily by ventricular reflux and stasis and secondarily by diminution of the parasagittal blush and a periventricular rim of decreased absorption. The intermediate group had minimal ventricular stasis after 24 hours and a normal parasagittal blush. After clinical and biochemical evaluation of the patient with dementia, CT scanning is usually indicated. If a profile suggestive of communicating hydrocephalus emerges, CSF kinetics can be monitored dynamically by CT scanning with metrizamide enhancement.

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References

  1. Hakim, S., Adams, R. D.: The special clinical problem of symptomatic hydrocephalus with normal CSF pressure; observations of CSF hydrodynamics. J. Neurol. Sci. 2, 307–327 (1965)

    Google Scholar 

  2. DiChiro, G., Reames, P. M., Mathews, W. B.: RISA ventriculography and RISA cisternography. Neurology 14, 185–191 (1964)

    Google Scholar 

  3. Benson, D. F., LeMay, M., Patton, D. H., et al.: Diagnosis of normal pressure hydrocephalus. N. Engl. J. Med. 283, 609–615 (1970)

    Google Scholar 

  4. Katzman, R., Hussey, F.: A simple constant-infusion manometric test for measurement of CSF absorption: I. Rationale and method. Neurology 20, 534–544 (1970)

    Google Scholar 

  5. Hounsfiled, G. N.: Computerized transverse axial scanning (tomography). Part I. Description of system. Brit. J. Radiol. 46, 1016–1022 (1973)

    Google Scholar 

  6. Ambrose, J.: Computerized transverse axial scanning (tomography). Part 2. Clinical application. Brit. J. Radiol. 46, 1023–1047 (1973)

    Google Scholar 

  7. Jacobs, L., Kinkel, W.: Computerized axial transverse tomography in normal pressure hydrocephalus. Neurology 26, 501–507 (1976)

    Google Scholar 

  8. Gado, M. H., Coleman, R. E., Lee, K. S., et al.: Correlation between computerized transaxial tomography and radionuclide cisternography in dementia. Neurology 26, 555–560 (1976)

    Google Scholar 

  9. Trotter, J. L., Lugecky, M., Siegel, B.: Cerebrospinal fluid infusion test. Neurology 24, 181–186 (1974)

    Google Scholar 

  10. James, A. E.: Cerebrospinal fluid imaging (Cisternography). Diagnostic Nuclear Medicine. pp. 303–331. A. Gottschalk, E. J. Potchen (eds.). Baltimore: Williams and Wilkins 1976

    Google Scholar 

  11. Metrizamide 1973: Metrizamide-A non-ionic water-soluble contrast medium. Acta radiol. diagn. (Suppl.) 335, 1–390 (1973)

    Google Scholar 

  12. Greitz, T., Hindmarsh, T.: Computer assisted tomography of intracranial CSF circulation using a watersoluble contrast medium. Acta radiol. diagn. 15, 497–507 (1974)

    Google Scholar 

  13. Malis, L. I.: The myelographic examination of the foramen magnum. Radiology 70, 196–212 (1958)

    Google Scholar 

  14. James, A. E., New, P. F. J., Heinz, E. R., Hodges, F. J., Deland, F. H.: A cisternographic classification of hydrocephalus. Amer. J. Roentgenol. 115, 39–49 (1972)

    Google Scholar 

  15. Nielsen, H.: Epileptic seizures following cervical myelography. Neuroradiology 10, 59–60 (1975)

    Google Scholar 

  16. Ambrose, I., Gooding, M. R., Richardson, A. E.: Sodium iothalamateas an aid to diagnosis of intracranial lesions by computerized transverse axial scanning. Lancet 2, 669–674 (1975)

    Google Scholar 

  17. Gado, M. H., Phelps, M. E., Coleman, R. E.: An extravascular component of contrast enhancement in cranial computed tomography. Part II. Contrast enhancement and the blood-tissue barrier. Radiology 117, 595–597 (1975)

    Google Scholar 

  18. Kramer, R. A., Janetas, G. P., Perlstein, G.: An approach to contrast enhancement in computed tomography of the brain. Radiology 116, 641–647 (1975)

    Google Scholar 

  19. Arnell, S., Lidström, F.: Myelography with Skiodil (abrodil). Acta radiol. 12, 287–298 (1931)

    Google Scholar 

  20. Levitan, H., Rapoport, S. I.: Contrast Media, Quantitative criteria for designing compounds with low toxicity. Acta radiol. diag. (Suppl.) 335, 67–83 (1973)

    Google Scholar 

  21. Sawhney, B. B., Oftedal, S. I.: Reactions of suboccipital injection of watersoluble contrast media in rabbits. Acta radiol. diag. (Suppl.) 335, 67–83 (1973)

    Google Scholar 

  22. Hindmarsh, T., Grepe, A., Widen, L.: Metrizamidephenothiazine interaction. Report of a case with seizures following myelography. Acta radiol. diag. 16, 129–134 (1975)

    Google Scholar 

  23. Hindmarsh, T.: Lumbar myelography with meglumine iocarmate with metrizamide. Acta radiol. diag. 16, 209–222 (1975)

    Google Scholar 

  24. Grepe, A., Widen, L.: Effects of cisternal application of metrizamide. Acta radiol. diag. (Suppl.) 335, 119–124 (1973)

    Google Scholar 

  25. Wylie, I. G., Afshar, F., Koege, T. H.: Results of the use of a new watersoluble contrast medium (metrizamide) in the posterior fossa of the baboon. Brit. J. Radiol. 48, 1007–1010 (1975)

    Google Scholar 

  26. Daly, D. D.: Genesis of abnormal activity. Handbook of Electroencephalography and Clinical Neurophysiology. Volume 14, pp. 5–10. A. Redmond (ed.). Amsterdam: Elsevier 1975

    Google Scholar 

  27. Gonsette, R. E.: Metrizamide as contrast medium for myelography and ventriculography. Acta radiol. diag. (Suppl.) 335, 346–358 (1973)

    Google Scholar 

  28. DiChiro, G.: Movement of the cerebrospinal fluid in human beings. Nature 204, 290–291 (1964)

    Google Scholar 

  29. McAfee, I. G., Subramanian, G.: Radioactive agents for imaging. p. 82. A. Gottschalk, E. J. Potchen (eds.). New York: Grune and Stratton 1975

    Google Scholar 

  30. Messert, B., Wannamaker, B. B.: Reappraisal of the adult occult hydrocephalus syndrome. Neurology 24, 224–231 (1974)

    Google Scholar 

  31. Wood, J. H. M., Detlef, B., James, A. E.: Normal-pressure hydrocephalus: Diagnosis and patient selection for shunt surgery. Neurology 24, 517–526 (1974)

    Google Scholar 

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Drayer, B.P., Rosenbaum, A.E. & Higman, H.B. Cerebrospinal fluid imaging using serial metrizamide CT cisternography. Neuroradiology 13, 7–17 (1977). https://doi.org/10.1007/BF00335029

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