Skip to main content
SpringerLink
Log in

Etude de la cholangiogénèse chez le foetus humain

I. Aspects ultrastructuraux et classification des divers types cellulaires épithéliaux rencontrés dans les régions périportales

  • Published:
Zeitschrift für Zellforschung und Mikroskopische Anatomie Aims and scope Submit manuscript

Summary

The fine structure of the different cells at the margin of the portal spaces was investigated in the foetal human liver. Two types of cells intermediate between biliary epithelial and parenchymal elements were described.

In addition, a type of cell in which both the cytoplasm and nucleus are electron-dense was observed. This element is different from the dark cell of Steiner et al. (1962b).

Résumé

Les auteurs, étudiant les diverses cellules épithéliales rencontrées dans la région périportale du foie foetal humain, décrivent deux types d'éléments qui possèdent des caractères ultrastructuraux intermédiaires entre ceux de la cellule épithéliale biliaire et ceux de l'hépatocyte.

Ils décrivent un type cellulaire à cytoplasme et noyau fortement denses, différents de ceux que l'on observe dans les «dark cells» de Steiner et coll. (1962b).

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Bibliographie

  • Albot, G., et A.-M. Jézéquel: Le passage entre les canalicules biliaires trabéculaires et les canaux biliaires interlobulaires chez l'homme. Etude ultra-microscopique. Presse méd. 70, 1495–1498 (1962).

    CAS  PubMed  Google Scholar 

  • Alexander, R. W., and J. W. Grisham: Light and electron microscopic study of rat liver cells in primary tissue culture. Gastroenterology 50, 390–391 (1966).

    Google Scholar 

  • Bruni, C., and K. R. Porter: The fine structure of the parenchymal cell of the normal rat liver. I. Amer. J. Path. 46, 691–755 (1965).

    CAS  PubMed  PubMed Central  Google Scholar 

  • Cammermeyer, J.: An evaluation of the significance on the “dark” neuron. Ergebn. Anat. Entwickl.-Gesch. 36, 1–61 (1962).

    CAS  Google Scholar 

  • Clara, M.: Untersuchungen an der menschlichen Leber. I. Z. mikr.-anat. Forsch. 20, 584–607 (1930).

    Google Scholar 

  • Daems, W. Th.: The micro-anatomy of the smallest biliary pathways in mouse liver tissue. Acta anat. (Basel) 46, 1–24 (1961).

    Article  CAS  Google Scholar 

  • Doljanski, L., u. Fr. Roulet: Über die gestaltende Wechselwirkung zwischen dem Epithel und dem Mesenchym, zugleich ein Beitrag zur Histogenese der sogenannten „Gallengangswucherungen“. Virchows Arch. path. Anat. 292, 256–267 (1934).

    Article  Google Scholar 

  • Fawcett, D. W.: Observations on the cytology and electron microscopy of hepatic cells. J. nat. Cancer Inst. 15, 1475–1503 (1955).

    CAS  PubMed  Google Scholar 

  • Grisham, J. W., and W. S. Hartroft: Morphologic identification by electron microscopy of “oval” cells in experimental hepatic degeneration. Lab. Invest. 10, 317–332 (1961).

    CAS  PubMed  Google Scholar 

  • Jézéquel, A.-M.: Microscopie électronique du foie normal. Path. et Biol. 10, 501–527 (1962).

    Google Scholar 

  • Leduc, E.: Cell modulation in liver pathology. J. Histochem. Cytochem. 7, 253–255 (1959).

    Article  CAS  PubMed  Google Scholar 

  • Picardi, R., Z. Madarasz, D. Gardiol e P. Magnenat: Alcuni aspetti della istogenesi epatica nell'uomo. Epatologia (sous presse).

  • Popper, H., F. Schaffner, F. Hutterer, F. Paronetto, and T. Barka: Parenchymal fibrogenesis: the liver. Ann. N. Y. Acad. Sci. 86, 1075–1088 (1960).

    Article  CAS  PubMed  Google Scholar 

  • Rouiller, C., and A.-M. Jézéquel: Electron microscopy of the liver. In: The liver, vol. I, p. 195–264. (C. Rouiller, éd). New York and London: Academic Press 1963.

    Google Scholar 

  • Schaffner, F., and H. Popper: Electron microscopic studies of normal and proliferated bile ductules. Amer. J. Path. 38, 393–410 (1961).

    CAS  PubMed  PubMed Central  Google Scholar 

  • Scharrer, E.: On dark and light cells in the brain and in the liver. Anat. Rec. 72, 53–65 (1938).

    Article  Google Scholar 

  • Steiner, J. W., and J. S. Carruthers: Studies on the fine structure of the terminal branches of the biliary tree. I. Amer. J. Path. 38, 639–661 (1961a).

    CAS  PubMed  PubMed Central  Google Scholar 

  • —: Studies on the fine structure of proliferated bile ductules. II. Canad. med. Ass. J. 85, 1275–1287 (1961b).

    CAS  PubMed  PubMed Central  Google Scholar 

  • —: Experimental extrahepatic biliary obstruction. Amer. J. Path. 40, 253–270 (1962a).

    CAS  PubMed  PubMed Central  Google Scholar 

  • —, and S. R. Kalifat: The ductular cell reaction of rat liver in extrahepatic cholestasis. I. Exp. mol. Path. 1, 162–185 (1962b).

    Article  CAS  Google Scholar 

  • Sternlieb, I.: Electron microscopic study of intrahepatic biliary ductules. J. Microscopie 4, 71–80 (1965).

    Google Scholar 

  • Yamada, K.: Ultrastructural features of the epithelium lining the intrahepatic bile ducts of normal and cholecystectomized mice. J. Cell Biol. 31, 166 A (1966).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Centre de Microscopie Electronique, Université de Lausanne, Switzerland

    R. Picardi, D. Gardiol & A. Gautier

  2. Institut d'Anatomie Pathologique, Université de Lausanne, Switzerland

    R. Picardi, D. Gardiol & A. Gautier

Authors
  1. R. Picardi
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. D. Gardiol
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. A. Gautier
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Travail subventionné par le «Fonds National Suisse de la Recherche Scientifique», requête N∘ 3731.

Avec la collaboration technique de Mme M. Schreyer et de Mlle M.-M. Bertholet.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Picardi, R., Gardiol, D. & Gautier, A. Etude de la cholangiogénèse chez le foetus humain. Z. Zellforsch. 84, 311–318 (1967). https://doi.org/10.1007/BF00334748

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00334748

Search

Navigation