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An estimate of the global error frequency in translation

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Summary

Electrophoretic heterogeneity in a set of selected proteins is used to estimate the average error frequency during translation. Estimates based upon streptomycin-induced heterogeneity as well as mistranslation of an ochre codon yield an average error frequency of 4x10-4 for normally growing cells.

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Authors and Affiliations

  1. Department of Genetics, University of Washington, 98195, Seattle, Washington, USA

    Nathan Ellis & Jonathan Gallant

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  1. Nathan Ellis
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  2. Jonathan Gallant
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Communicated by O. Siddiqi

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Ellis, N., Gallant, J. An estimate of the global error frequency in translation. Mol Gen Genet 188, 169–172 (1982). https://doi.org/10.1007/BF00332670

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  • DOI: https://doi.org/10.1007/BF00332670

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