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Homeosis and the interaction of zeste and white in Drosophila

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Summary

Transvection effects in Drosophila melanogaster suggest a form of gene modulation that is responsive to the proximity of homologous genes. These effects have been well characterized at bithorax and decapentaplegic, and in the interaction between the zeste and white genes. The mechanistic basis for transvection is not known. As part of a genetic analysis of transvection, a study is being made of a class of mutation defined as modifiers of the eye color resulting from the interaction of zeste and white. This report details the observations that several of these mutations also have homeotic effects.

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Author notes

  1. C.-ting Wu

    Present address: Department of Biology, Massachusetts Institute of Technology, 77 Massachusetts Avenue, 02139, Cambridge, MA, USA

  2. Paul F. Lasko

    Present address: Department of Genetics, University of Cambridge, Downing Street, CB2 3EH, Cambridge, UK

Authors and Affiliations

  1. SNS, 1530 Notch Road, 06410, Cheshire, CT, USA

    C.-ting Wu

  2. Department of Biology, Yale University, P.O. Box 6666, 06511-8112, New Haven, CT, USA

    C.-ting Wu

  3. Department of Cellular and Developmental Biology, The Biological Laboratories, Harvard University, 16 Divinity Avenue, 02138, Cambridge, MA, USA

    C.-ting Wu, Richard S. Jones & William M. Gelbart

  4. Department of Molecular Biology, Massachusetts General Hospital, 02114, Boston, MA, USA

    Paul F. Lasko

  5. Department of Genetics, Harvard Medical School, USA

    Paul F. Lasko

Authors
  1. C.-ting Wu
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  2. Richard S. Jones
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  3. Paul F. Lasko
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  4. William M. Gelbart
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Communicated by B.H. Judd

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Wu, Ct., Jones, R.S., Lasko, P.F. et al. Homeosis and the interaction of zeste and white in Drosophila . Mol Gen Genet 218, 559–564 (1989). https://doi.org/10.1007/BF00332424

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  • DOI: https://doi.org/10.1007/BF00332424

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