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Mistranslation during phenylalanine starvation

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Summary

Starvation for phenylalanine led to leucine misincorporation frequencies of 0.1 and 0.6 at UUC codons in the argI transcript of Escherichia coli, but no detectable misincorporation at a UUU codon. Under similar starvation conditions the relative synthesis of full sized MS2 coat protein, encoded by the RNA virus or a DNA copy, is greatly reduced, preventing analysis of the protein. This reduction in amount is unaffected by a rpsL mutation.

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Communicated by A. Böck

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Parker, J., Precup, J. Mistranslation during phenylalanine starvation. Molec Gen Genet 204, 70–74 (1986). https://doi.org/10.1007/BF00330189

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