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Human spinal arachnoid villi and granulations

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Summary

Human spinal arachnoid villi and granulations were studied after distension by a subarachnoid perfusion of Berlin blue and trypan blue. These proliferations were distributed on almost every nerve root in the thoracic and lumbar region. Human spinal arachnoid villi and granulations were divided into those located entirely internal to the dura, those that extended into the dura, and those that penetrated the dura completely. Venous sinuses were closely related to most arachnoid proliferations.

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References

  1. Key, E. A. H., Retzius, G.: Studien in der Anatomie des Nervensystems und des Bindegewebes. Stockholm: Samson and Wallin 1875–1876

  2. Weed, L. H.: Studies on cerebro-spinal fluid. No. III. The pathways of escape from the subarachnoid spaces with particular reference to the arachnoid villi. J. Med. Res. 31, 51–91 (1914)

    Google Scholar 

  3. Davson, H.: Physiology of the Cerebrospinal Fluid. London: Churchill 1967

    Google Scholar 

  4. Di Chiro, G., Larson, S. M., Harrington, T., Johnston, G. S., Green, M. V., Swann, S. J.: Descent of cerebrospinal fluid to spinal subarachnoid space. Acta radiol. (diagn.) 14, 379–384 (1973)

    Google Scholar 

  5. Lorenzo, A. V., Hammerstad, J. P., Cutler, R. W. P.: Cerebrospinal fluid formation and absorption and transport of iodide and sulfate from the spinal subarachnoid space. J. Neurol. Sci. 10, 247–258 (1970)

    Google Scholar 

  6. Murray, J. E., Cutler, R. W. P.: Short communication: Clearance of glycine from cat cerebrospinal fluid: faster clearance from spinal subarachnoid than from ventricular compartment. J. Neurochem. 17, 703–704 (1970)

    Google Scholar 

  7. Brierley, J. B., Field, E. J.: The connexions of the spinal subarachnoid space with the lymphatic system. J. Anat. Lond. 82, 153–166 (1948)

    Google Scholar 

  8. Wright, G. P.: Nerve trunks as pathways in infection. Proc. Roy. Soc. Med. 46, 319–330 (1953)

    Google Scholar 

  9. Elman, R.: Spinal arachnoid granulations with especial reference to the cerebrospinal fluid. Johns Hopkins Hosp. Bull. 34, 99–104 (1923)

    Google Scholar 

  10. Hassin, G. B.:Villi (Pacchionian bodies) of the spinal arachnoid. Arch. Neurol. Psychiat. 23, 65–78 (1930)

    Google Scholar 

  11. Wislocki, G. B.: The cytology of the cerebrospinal pathway. In: Special Cytology, E. V. Cowdry, ed., 2nd ed., Vol. III. pp. 1483–1521. New York: Hoeber 1932

    Google Scholar 

  12. Woollam, D. H. M., Millen, J. W.: Observations on the production and circulation of the cerebrospinal fluid. In: Ciba Foundation Symposium on the Cerebrospinal Fluid: Production, circulation and absorption. G. E. W. Wolstenholme and C. M. O'Connor, eds. pp. 124–142. Boston: Little, Brown 1958

    Google Scholar 

  13. Potts, D. G., Deonarine, V., Welton, W.: Perfusion studies of the cerebrospinal fluid absorptive pathways in the dog. Radiology 104, 321–325 (1972)

    Google Scholar 

  14. Gomez, D. G., Chambers, A. A., Di Benedetto, A. T., Potts, D. G.: The spinal cerebrospinal fluid absorptive pathways. Neuroradiology 8, 61–66 (1974)

    Google Scholar 

  15. Ruddell, C. L.: Embedding media for 1–2 micron sectioning 2. Hydroxyethyl methacrylate combined with 2-butoxyethanol. Stain. Technol. 42, 253–255 (1967)

    Google Scholar 

  16. McCabe, J. S., Low, F. N.: The subarachnoid angle: An area of transition in peripheral nerve. Anat. Rec. 164, 15–33 (1969)

    Google Scholar 

  17. Welch, K., Pollay, M.: The spinal arachnoid villi of the monkeys Cercopithecus aethiops sabaeus and Macaca irus. Anat. Rec. 145, 43–48 (1963)

    Google Scholar 

  18. Welch, K., Friedman, V.: The cerebrospinal fluid valves. Brain 83, 454–469 (1960)

    Google Scholar 

  19. Pollay, M.: CSF formation and mechanism of drainage. In: Cisternography and Hydrocephalus — A Symposium. J. C. Harbert, ed. pp. 13–24. Springfield, Ill.: Thomas 1972

    Google Scholar 

  20. Abel, J. J., Evans, E. A., Jr., Hampil, B., Lee, F. C.: Researches on tetanus. II. The toxin of the bacillus tetani is not transported to the central nervous system by any component of the peripheral nerve trunks. Johns Hopkins Hosp. Bull. 56, 84–114 (1935)

    Google Scholar 

  21. Burkel, W. E.: The histological fine structure of perineurium. Anat. Rec. 158, 177–189 (1967)

    Google Scholar 

  22. Howarth, F., Cooper, E. R. A.: The fate of certain foreign colloids and crystalloids after subarachnoid injection. Acta Anat. 25, 112–140 (1955)

    Google Scholar 

  23. Gomez, D. G., Potts, D. G., Deonarine, V.: Arachnoid granulations of the sheep; structural and ultrastructural changes with varying pressure differences. Arch. Neurol. 30, 169–175 (1974)

    Google Scholar 

  24. Alksne, J. F., White, L. E., Jr.: Electro-microscope study of the effect of increased intracranial pressure on the arachnoid villus. J. Neurosurg. 22, 481–488 (1965)

    Google Scholar 

  25. Shabo, A. L., Maxwell, D. S.: Electron microscopic observations on the fate of particulate matter in the cerebrospinal fluid. J. Neurosurg. 29, 464–474 (1968)

    Google Scholar 

  26. Tripathi, B. J., Tripathi, R. C.: Vacuolar transcellular channels as a drainage pathway for cerebrospinal fluid. J. Physiol. 239, 195–206 (1974)

    Google Scholar 

  27. Gomez, D. G., Potts, D. G., Deonarine V., Reilly, K. F.: Effects of pressure gradient changes on the morphology of arachnoid villi and granulations of the monkey. Lab. Invest 28, 648–657 (1973)

    Google Scholar 

  28. Potts, D. G., Deonarine, V.: Effect of positional changes and jugular vein compression on the pressure gradient across the arachnoid villi and granulations of the dog. J. Neurosurg. 38, 722–728 (1973)

    Google Scholar 

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This investigation was supported by the National Institutes of Health Research Grant No. 2-RO1-NS09198-04.

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Kido, D.K., Gomez, D.G., Pavese, A.M. et al. Human spinal arachnoid villi and granulations. Neuroradiology 11, 221–228 (1976). https://doi.org/10.1007/BF00328377

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  • DOI: https://doi.org/10.1007/BF00328377

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