Summary
The EORTC Genito-Urinary Group has recruited patients into three major phase III trials of the endocrine treatment of advanced prostatic cancer. In terms of time to progression and length of survival, there is no significant difference between any of the effective endocrine treatments that have been studied. As well as these factors, the clinician has to consider treatment toxicity, relief of symptoms and quality of life when he considers the optimal endocrine management for metastatic prostatic cancer. The EORTC studies have not demonstrated that any alternative hormonal therapy is superior to orchidectomy which is not costly and does not produce life-threatening complications.
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Robinson, M.R.G., Hetherington, J. The EORTC studies: is there an optimal endocrine management for M1 prostatic cancer?. World J Urol 4, 171–175 (1986). https://doi.org/10.1007/BF00327015
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DOI: https://doi.org/10.1007/BF00327015