Abstract
The translation elongation factor EF-1α appears to play a major role in the control of cell proliferation and ageing in higher eukaryotes. Here we report the cloning of the TEF1 gene encoding the elongation factor 1α of the dimorphic yeast Arxula adeninivorans Ls3. The gene is localized on chromosome 2 from Arxula adeninivorans, comprises 1380 bp and encodes a protein containing 459 amino acids. In contrast to other fungi, a second TEF gene encoding an identical, or nearly identical, polypeptide could not be identified. The transcriptional activity of the TEF1 gene did not change during mycelial growth, whereas a slight decrease could be detected during the yeast growth.
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Communicated by K. Wolf
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Rösel, H., Kunze, G. Cloning and characterization of a TEF gene for elongation factor 1α from the yeast Arxula adeninivorans . Curr Genet 28, 360–366 (1995). https://doi.org/10.1007/BF00326434
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DOI: https://doi.org/10.1007/BF00326434