Abstract
The occurrence of discrete transcripts originating from the non-coding strand of the yeast mitochondrial genome is described. The region under investigation is localized in the large tRNA gene cluster between the LSU ribosomal RNA and OXI1 genes. The transcripts originating from the non-coding strand were detected in a wild-type strain and in a rho - mutant. Their size range includes transcripts of about 2000 nucleotides able to accommodate more than one “anti-tRNA”. In some cases their extremities can be mapped near highly-conserved nonanucleotides that could function as origins of transcription. The involvement of the tRNA-processing machinery in the cleavage of these transcripts is also hypothesized.
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Communicated by R. J. Schweyen
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Grisanti, P., Francisci, S., Tataseo, P. et al. Symmetrical transcription in the tRNA region of the mitochondrial genome of Saccharomyces cerevisiae . Curr Genet 24, 122–125 (1993). https://doi.org/10.1007/BF00324675
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DOI: https://doi.org/10.1007/BF00324675