Summary
C'3 phenotype and gene frequencies observed in two Italian samples are reported. The allele frequencies resemble those reported for other Caucasian populations. Five different rare variants are described.
Similar content being viewed by others
References
Alper, C. A., Propp, R. P.: Genetic polymorphism of the third component of human complement (C'3). J. Clin. Invest. 47, 2181–2191 (1968)
Alper, C. A., Rosen, F. S.: Genetics of the complement system. Adv. Hum. Genet. 7, 141–188 (1976)
Harris, H., Hopkinson, D. A., Robson, E. B.: The incidence of rare alleles determining electrophoretic variants: data on 43 enzyme loci in man. Ann. Hum. Genet. 37, 237–253 (1974)
Rittner, C., Rittner, B.: Report 1973/74 of the Reference Laboratory for the Polymorphism of the Third Component (C'3) of the Human Complement System. Vox Sang. 27, 464–472 (1974)
Seth, P. K., Seth, S.: Human complementary component C'3. Hum. Genet. 33, 201–211 (1976)
Teisberg, P.: High voltage agarose gel electrophoresis in the study of C3 polymorphism. Vox Sang. 19, 47–56 (1970)
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Scacchi, R., Corbo, R.M., Spennati, G. et al. C′3 polymorphism in Italy. Hum Genet 47, 335–337 (1979). https://doi.org/10.1007/BF00321026
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00321026