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High-dose IgG treatment for neonatal alloimmune thrombocytopenia

  • Proceedings Of The International Workshop On ITP
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Summary

Twelve children with neonatal alloimmune thrombocytopenia (NAT) due to Zwa incompatibility were treated with intravenous IgG (IVIG). Total doses ranged between 1 and 9 g. Ten out of 12 infants had a favorable response. It is concluded that IVIG can serve as an emergency treatment in NAT if material (or compatible) platelets are not available.

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Authors and Affiliations

  1. Institute for Clinical Immunology and Transfusion Medicine, Justus-Liebig-University, Langhansstrasse 7, D-6300, Giessen, Germany

    Christian Mueller-Eckhardt, Volker Kiefel & Alfons Grubert

Authors
  1. Christian Mueller-Eckhardt
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  2. Volker Kiefel
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  3. Alfons Grubert
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Additional information

This work was supported by the Deutsche Forschungsgemeinschaft (Mu 277/9–6)

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Mueller-Eckhardt, C., Kiefel, V. & Grubert, A. High-dose IgG treatment for neonatal alloimmune thrombocytopenia. Blut 59, 145–146 (1989). https://doi.org/10.1007/BF00320268

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  • DOI: https://doi.org/10.1007/BF00320268

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