Summary
The nerve fibres of the corpus callosum were studied by electron microscopy in five elderly patients with progressive subcortical vascular encephalopathy (PSVE) and compared with those in six age-matched controls. The number of nerve fibres per unit area of the corpus callosum was decreased in PSVE by 18–26%. The loss of nerve fibres in the corpus callosum can play a role in inducing the cognitive deficit of PSVE, on the basis of the loss of nerve fibres in the cerebral hemispheres.
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Yamanouchi, H., Sugiura, S. & Shimada, H. Loss of nerve fibres in the corpus callosum of progressive subcortical vascular encephalopathy. J Neurol 237, 39–41 (1990). https://doi.org/10.1007/BF00319666
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DOI: https://doi.org/10.1007/BF00319666