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Amyloid angiopathy and granulomatous angiitis of the central nervous system: a case responding to corticosteroid treatment

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Summary

A 73-year-old woman presented with multifocal cerebral dysfunction of 1 month's duration. Cranial CT scanning revealed unusual widespread abnormalities. Brain biopsy showed amyloid angiopathy affecting vessels in the meninges and cerebral cortex, with associated granulomatous angiitis. There was no clinical evidence of extracranial vasculitis. Corticosteroid therapy produced striking clinical and radiological improvement.

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Authors and Affiliations

  1. Department of Neurology, Royal Free Hospital, NW32QG, London, UK

    L. Ginsberg

  2. Department of Histopathology, Royal Free Hospital, NW32QG, London, UK

    J. Geddes

  3. Department of Radiology, Royal Free Hospital, NW32QG, London, UK

    A. Valentine

Authors
  1. L. Ginsberg
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  2. J. Geddes
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  3. A. Valentine
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Ginsberg, L., Geddes, J. & Valentine, A. Amyloid angiopathy and granulomatous angiitis of the central nervous system: a case responding to corticosteroid treatment. J Neurol 235, 438–440 (1988). https://doi.org/10.1007/BF00314491

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  • DOI: https://doi.org/10.1007/BF00314491

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