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Fibre density, amplitudes of macro-EMG motor unit potentials and conventional EMG recordings from the anterior tibial muscle in patients with amyotrophic lateral sclerosis

A study on 51 cases

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Summary

Fibre density and amplitudes of macro-EMG motor unit potentials were studied and compared with conventional EMG in the anterior tibial muscles from 51 patients with amyotrophic lateral sclerosis. The fibre density was increased in 46 muscles. Increased amplitudes of macro-EMG motor unit action potentials were found in 46 muscles, while the mean duration of motor unit potentials recorded with a concentric needle electrode was prolonged in only 26 muscles. Changes in the packing density of muscle fibres of surviving motor units are thought to influence the different electrophysiological parameters in different ways.

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References

  1. Ballantyne JP, Hansen S (1974) Computer method for the analysis of evoked motor unit potentials. 1. Control subjects and patients with myasthenia gravis. J Neurol Neurosurg Psychiatry 37:1187–1194

    Google Scholar 

  2. Buchthal F (1957) An introduction to electromyography. Scandinavian University Books, Gyldendal, Copenhagen

    Google Scholar 

  3. Buchthal F, Kamieniecka Z (1982) The diagnostic yield of quantified electromyography and quantified muscle biopsy in neuromuscular disorders. Muscle Nerve 5:265–280

    Google Scholar 

  4. Buchthal F, Pinelli P (1952) Analysis of muscle action potentials as a diagnostic aid in neuro-muscular disorders. Acta Neurol Scand [Suppl] 266:315–327

    Google Scholar 

  5. Buchthal F, Pinelli P (1953) Action potentials in muscular atrophy of neurogenic origin. Neurology 3:591–603

    Google Scholar 

  6. Coërs C, Telerman-Toppet N, Gerard JM (1973). Terminal innervation ratio in neuromuscular disease. 2. Disorders of lower motor neurone, peripheral nerve and muscle. Arch Neurol 29:215–222

    Google Scholar 

  7. Dubowitz V, Brooke MH (1973) Muscle biopsy: a modern approach. Saunders, Philadelphia

    Google Scholar 

  8. Engel AG, Banker BQ (1986) Myology. McGraw-Hill, New York

    Google Scholar 

  9. Erminio F, Buchthal F, Rosenfalck P (1959) Motor unit territory and muscle fibre concentration in paresis due to peripheral nerve injury and anterior horn cell involvement. Neurology 9:657–671

    Google Scholar 

  10. Fawcett PRW, Johnson MA, Schofield IS (1985) Comparison of electrophysiological and histochemical methods for assessing the spatial distribution of muscle fibres of a motor unit within a muscle. J Neurol Sci 69:67–79

    Google Scholar 

  11. Hansen S, Ballantyne JP (1978) A quantitative electrophysiological study of motor neurone disease. J Neurol Neurosurg Psychiatry 41:773–783

    Google Scholar 

  12. Hilton-Brown P, Stålberg E (1983) The motor unit in muscular dystrophy: a single fibre EMG and scanning EMG study. J Neurol Neurosurg Psychiatry 46:981–995

    Google Scholar 

  13. Ludin HP (1980) Electromyography in practice. Thieme-Stratton. New York

    Google Scholar 

  14. McComas AJ, Fawcett PRW, Campbell MJ, Sica REP (1971) Electrophysiological estimation of the number of motor units within a human muscle. J Neurol Neurosurg Psychiatry 34:121–131

    Google Scholar 

  15. McComas AJ, Sica REP, Campbell MJ, Upton ARM (1971) Functional compensation in partially denervated muscles. J Neurol Neurosurg Psychiatry 34:453–460

    Google Scholar 

  16. Nandedkar S, Stålberg E (1983) Simulation of macro EMG motor unit potentials. Electroencephalogr Clin Neurophysiol 56:52–62

    Google Scholar 

  17. Nandedkar S, Sanders DB, Stålberg E (1984) Simulation of concentric needle EMG motor unit action potentials. Muscle Nerve 7:562

    Google Scholar 

  18. Schwartz MS, Stalberg E, Swash M (1980) Pattern of segmental motor involvement in syringomyelia: a single fibre study. J Neurol Neurosurg Psychiatry 43:150–155

    Google Scholar 

  19. Stålberg E (1980) Macro EMG, a new recording technique. J Neurol Neurosurg Psychiatry 43:475–482

    Google Scholar 

  20. Stålberg E (1982) Electrophysiological studies of reinnervation in ALS. In: Rowland LP (ed) Human motor neuron diseases. Raven Press, New York, pp 47–59

    Google Scholar 

  21. Stålberg E (1983) Macro EMG. Muscle Nerve 6:619–630

    Google Scholar 

  22. Stålberg E, Fawcett PRW (1982) Macro EMG in healthy subjects of different ages. J Neurol Neurosurg Psychiatry 45:870–878

    Google Scholar 

  23. Stålberg E, Thiele B (1975) Motor unit fibre density in the extensor digitorum communis muscle. J Neurol Neurosurg Psychiatry 38:874–880

    Google Scholar 

  24. Stålberg E, Trontelj JV (1979) Single fibre electromyography. Mirvalle Press, Old Woking, Surrey

    Google Scholar 

  25. Stålberg E, Schwartz MS, Trontelj JV (1975) Single fibre electromyography in various processes affecting the anterior horn cell. J Neurol Sci 24:403–415

    Google Scholar 

  26. Stålberg E, Hilton-Brown P, Rydin E (1986) Capacity of the motor neuron to alter its peripheral field. In: Dimitrijevic M, Kakulas B, Vrbova (eds) Restorative procedures in neuromuscular diseases. Karger, Basel, pp 237–253

    Google Scholar 

  27. Swash M, Schwartz MS (1982) A longitudinal study of changes in motor units in motor neuron disease. J Neurol Sci 56:185–197

    Google Scholar 

  28. Telerman-Toppet N, Coërs C (1978) Motor innervation and fiber type pattern in amyotrophic lateral sclerosis and in Charcot-Marie-Tooth disease. Muscle Nerve 1:133–139

    Google Scholar 

  29. Thage O (1974) Quadriceps weakness and wasting. A neurological, electrophysiological and histological study. Fadls, Copenhagen

    Google Scholar 

  30. Wiechers DO, Hubbell SL (1981) Late changes in the motor unit after acute poliomyelitis. Muscle Nerve 4:524–528

    Google Scholar 

  31. Wohlfart G (1957) Collateral regeneration from residual motor nerve fibres in ALS. Neurology 7:124–134

    Google Scholar 

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Tackmann, W., Vogel, P. Fibre density, amplitudes of macro-EMG motor unit potentials and conventional EMG recordings from the anterior tibial muscle in patients with amyotrophic lateral sclerosis. J Neurol 235, 149–154 (1988). https://doi.org/10.1007/BF00314305

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  • DOI: https://doi.org/10.1007/BF00314305

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