Summary
A case of multiple sclerosis and Hashimoto's thyroiditis confirmed by cytology is reported. The association of multiple sclerosis with other autoimmune diseases is infrequent but supports the immune hypothesis of the pathogenesis of multiple sclerosis. The authors suggest the inclusion of immunological tests in the screening of all patients diagnosed as having multiple sclerosis.
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Achari AN, Trontelj JV, Campos RJ (1976) Multiple sclerosis and myasthenia gravis. A case with single fibre electromyography. Neurology 26:544–546
Aita JF, Snyder DH, Reichl W (1974) Myasthenia gravis and multiple sclerosis: an unusual combination of diseases. Neurology 24:72–75
Baker HWJ, Balla JI, Burger HG, Elbing P, McKay IR (1972) Multiple sclerosis and autoimmune disease. Aust NZ J Med 3:256–260
Bastente PA, Bonhyns M, Vanhaelst L, Neve P (1972) Diseases associated with autoimmune thyroiditis. In: Basteine P, Ermas EM (eds) Thyroiditis and thyroid function. Pergamon Press, Oxford
Cendrowski W (1975) A case of multiple sclerosis associated with defective neuromuscular transmission. Acta Neurol Belg 75:11–14
Crowe JP, Christensen F, Botler J, Wheeler P, Doniach D, Kennan J, Williams R (1980) Primary biliary cirrhosis: the prevalence of hypothyroidism and its relationship to thyroid auto-antibodies and sicca syndrome. Gastroenterology 78:1437–1441
Green JRB, Snitcher EJ, Mowat NAG, Ekins RP, Rees LH, Dawson A (1977) Thyroid function and thyroid regulation in euthyroid men with chronic liver disease: evidence of multiple abnormalities. Clin Endocrinol (Oxf) 7:453–461
Holmes FF, Stubbs DW, Larsen WE (1967). Systemic lupus erythematosus and multiple sclerosis in identical twins. Arch Int Med 119:302–304
Keane JR, Heyet WF (1970) Myasthenic vertical nystagmus. Verification by edrophonium tomography. JAMA 212:1209–1210
Kerschner M (1950) The effect of injuries and illness on the course of multiple sclerosis. Res Publ Assoc Nerv Ment Dis 28:533
Lo R, Feasby TE (1983) Multiple sclerosis and autoimmune diseases. Neurology 33:97–98
Margolis LN, Graves RW (1945) The occurrence of myasthenia gravis in a patient with multiple sclerosis. N C Med J 6:243–244
Mulhern LM, Masi AT, Shulman LE (1966) Hashimoto's disease. A search for associated disorders in 170 clinically detected cases. Lancet II: 508–511
Patten MB, Hart A, Lovelace R (1972). Multiple sclerosis associated with defects in neuromuscular transmission. J Neurol Neurosurg Psychiatry 35:385–394
Poser CH, Paty DW, Scheinberg L, McDonald WI, Davis FA, Ebers GC, Johnson KP, Sibley WA, Silberberg DH, Tourtellotte WW (1983) New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann Neurol 13:227–231
Read AE, Sherlock S, Harrison CV (1963) Active “juvenile” cirrhosis considered as part of a systemic disease and the effect of corticosteroid therapy. Cut 4:378
Riley WJ, McLaren NK, Lezotte DC, Spillar KP, Rosembloom AL (1981) Thyroid autoimmunity in insulin dependent diabetes mellitus: the case for routine screening. J Pediatr 98:350–354
Shakir RA, Hussein JM, Trontelj JV (1983) Myasthenia gravis and multiple sclerosis. J Neuroimmunol 4:161–165
Simpson JA (1964) Immunological disturbances in myasthenia gravis with a report of Hashimoto's disease developing after thymectomy. J Neurol Neurosurg Psychiatry 27:485–492
Simpson JA (1966) The biochemistry of myasthenia gravis. In: Kuhn E (ed) Progressive Muskeldystrophie, Myotonie und Myasthenie. Springer, Berlin
Taillan LB, Pedinielli FJ, Blanc AP, Micetto G (1985) Association familiale sclerose en plaques purpura thrombopenique chronique. Press Med 14:700
Waksman BM, Reynolds WE (1984) Multiple sclerosis as a disease of immune regulation. Proc Soc Exp Biol Med 175:282–294
Warrens S, Warrens KG (1981) Multiple sclerosis and associated disease: a relationship to diabetes mellitus. Can J Neurol Sci 8:35–39
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Roquer, J., Escudero, D., Herraiz, J. et al. Multiple sclerosis and Hashimoto's thyroiditis. J Neurol 234, 23–24 (1987). https://doi.org/10.1007/BF00314004
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DOI: https://doi.org/10.1007/BF00314004