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Cerebral granulomatous angiitis with atypical features

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Summary

A case of cerebral granulomatous angiitis of the left temporal lobe mimicking a brain tumour is presented. Following surgical removal of a glioma-imitating mass, histological examination disclosed a granulomatous vasculitis. Treatment consisted of dexamethasone given in tapering doses for 5 days after surgery. Clinical and morphological differences from other reported cases of granulomatous angiitis of the nervous system are described.

Zusammenfassung

Es wird über einen Fall von zerebraler granulomatöser Angiitis des linken Schläfenlappens berichtet, der zunächst für einen Hirntumor gehalten wurde. Nach der operativen Entfernung von gliomatös anmutendem Gewebe wurde histologisch die Diagnose einer granulomatösen Vaskulitis gestellt. Medikamentös wurde lediglich Dexamethason in fallender Dosierung während der ersten fünf postoperativen Tage verabreicht. Auf klinische und morphologische Unterschiede zu bisher publizierten Fällen von granulomatöser Angiitis des Nervensystems wird näher eingegangen.

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References

  1. Arthur G, Margolis G (1977) Mycoplasma-like structures in granulomatous angiitis of the central nervous system: case reports with light and electron microscopic studies. Arch Pathol Lab Med 101:382–387

    Google Scholar 

  2. Beresford HR, Hyman RA, Sharer L (1979) Selflimited granulomatous angiitis of the cerebellum. Ann Neurol 5:490–492

    Google Scholar 

  3. Blue MC, Rosenblum WI (1983) Granulomatous angiitis of the brain with herpes zoster and varicella encephalitis. Arch Pathol Lab Med 107:126–128

    Google Scholar 

  4. Budzilovich GN, Feigin I, Siegel H (1963) Granulomatous angiitis of the nervous system. Arch Pathol 76:250–256

    Google Scholar 

  5. Burger PC, Burch JG, Vogel FS (1977) Granulomatous angiitis: an unusual etiology of stroke. Stroke 8:29–35

    Google Scholar 

  6. De Reuck J, Crevits L, Sieben G, De Coster W, Eecken van der H (1982) Granulomatous angiitis of the nervous system: a clinicopathological study of one case. J Neurol 227:49–53

    Google Scholar 

  7. Faer MJ, Mead JH, Lynch RD (1977) Cerebral granulomatous angiitis: case report and literature review. Am J Roentgenol 129:463–467

    Google Scholar 

  8. Girard PL, Dumas M, Escourolle R, Ciudad A, Gray F, Ndiaye IP (1976) Angéite granulomateuse à cellules géantes du systême nerveux central. Rev Neurol (Paris) 132:369–382

    Google Scholar 

  9. Greco AF, Kolins J, Rajjoub RK, Brereton HD (1976) Hodgkin's disease and granulomatous angiitis of the central nervous system. Cancer 38:2027–2032

    Google Scholar 

  10. Griffin J, Price DL, Davis L (1973) Granulomatous angiitis of the central nervous system with aneurysms on multiple cerebral arteries. Trans Am Neurol Assoc 98:145–148

    Google Scholar 

  11. Harrison PE Jr (1976) Granulomatous angiitis of the central nervous system: case report and review. J Neurol Sci 29:335–341

    Google Scholar 

  12. Jellinger K (1977) Giant cell granulomatous angiitis of the central nervous system. J Neurol 215:175–190

    Google Scholar 

  13. Kessler C, Berlit P, Reuther R, Schwechheimer K (1983) Zur Differentialdiagnose der Thrombangiitis obliterans v. Winiwarter-Buerger. Nervenarzt 54:85–91

    Google Scholar 

  14. Kolodny EH, Rebeiz JJ, Caviness VS Jr, Richardson EP Jr (1968) Granulomatous angiitis of the central nervous system. Arch Neurol 19:510–524

    Google Scholar 

  15. Liang G, Simkin PA, Mannik M (1974) Immunoglobulines in temporal arteriitis. An immunofluorescent study. Ann Int Med 81:19–24

    Google Scholar 

  16. Newman W, Wolf A (1952) Non-infectous granulomatous angiitis involving the central nervous system. Trans Am Neurol Assoc 77:114–117

    Google Scholar 

  17. Nurick S, Blackwood W, Mair WGP (1972) Giant-cell granulomatous angiitis of the nervous system. Brain 95:133–142

    Google Scholar 

  18. Rajjoub RK, Wood JH, Ommaya AK (1977) Granulomatous angiitis of the brain: a successfully treated case. Neurology (Minneap) 27:588–591

    Google Scholar 

  19. Rawlison DG, Braun CW (1981) Granulomatous angiitis of the nervous system first seen as relapsing myelopathy. Arch Neurol 38:129–131

    Google Scholar 

  20. Rewcastle NB, Tom MI (1962) Non-infectous granulomatous angiitis of the nervous system associated with Hogdkin's disease. J Neurol Neurosurg Psychiatry 25:51–58

    Google Scholar 

  21. Rosenblum WI, Hadfield MG (1972) Granulomatous angiitis of the nervous system in cases of herpes zoster and lymphosarcoma. Neurology (Minneap) 22:348–354

    Google Scholar 

  22. Rottino A, Hoffman G (1950) A sarcoid form of encephalitis in a patient with Hodgkin's disease; case report with review of the literature. J Neuropathol Exp Neurol 9:103–108

    Google Scholar 

  23. Russie E, Aebi M, Krauss-Ruppert R, Mumenthaler M (1979) Intracranial giant cell arteritis. J Neurol 221:219–224

    Google Scholar 

  24. Sandhu R, Alexander WS, Hornabrook RW (1979) Granulomatous angiitis of the CNS. Arch Neurol 36:433–435

    Google Scholar 

  25. Sauerbruch T, Stuhlinger H, Kaess H (1973) Immunhistologische Untersuchungen bei einem Fall von Riesenzellarteriitis (Arteriitis temporalis). Dtsch Med Wochenschr 98:283–285

    Google Scholar 

  26. Scully RE, Galdabini JJ, McNeely BU (1976) Case records of the Massachusetts General Hospital: weekly clinicopathological exercises, case 43, 1976. N Engl J Med 295:944–950

    Google Scholar 

  27. Thomas L, Davidson M, McClusky RT (1966) Studies of PPLO infections. I. The production of cerebral polyarteritis by mycoplasma gallisepticum in turkeys; the neurotoxic property of mycoplasma. J Exp Med 123:897–912

    Google Scholar 

  28. Valvanis A, Friede R, Schubiger O, Hayek J (1979) Cerebral granulomatous angiitis simulating brain tumor. J Comput Assist Tomogr 3:536–538

    Google Scholar 

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Kristoferitsch, W., Jellinger, K. & Böck, F. Cerebral granulomatous angiitis with atypical features. J Neurol 231, 38–42 (1984). https://doi.org/10.1007/BF00313650

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