Abstract
We report herein an extremely rare case of retroperitoneal neuroblastoma occurring in a mother during her third trimester of pregnancy. A live male infant was delivered by cesarean section at 36 weeks gestation and 23 days later, the mother's tumor was curatively resected. Six months have elapsed since her operation and there has been no evidence of tumor recurrence. Adult neuroblastoma is an uncommon malignancy and, to our knowledge, there has been no case of this tumor occuring in pregnancy ever described in the English literature. The diagnosis, treatment, and follow-up of this neoplasm and its association with pregnancy are discussed in this report.
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Kaye JA, Warhol MJ, Kretschmar C, Landsberg L, Frei E (1986) Neuroblastoma in adults. Three cases report and a review of the literature. Cancer 58:1149–1157
Mackay B, Luna MA, Butler JJ (1976) Adult neuroblastoma. Electron microscopic observations in nine cases. Cancer 37:1334–1351
Allen SG, Cornbleet MA, Carmichael J, Arnott SJ, Smyth JF (1986) Adult neuroblastoma: Report of three cases and review of the literature. Cancer 57:2419–2421
Doisk GM, Rodriguez V, Benjamin RS, Bodey GP (1978) Neuroblastoma in the adult. Effective combination chemotherapy. Cancer 41:56–63
Cantin J, McNeer GP (1967) The effects of pregnancy upon the clinical course of sarcoma of the soft somatic tissue. Surg Gynecol Obstet 125:28–33
Grubb BP, Thant M (1984) Neuroblastoma in an adult. South Med J 77:1180–1182
Holland T, Donohue JP, Baehner R, Grosfeld JL (1980) The current management of neuroblastoma. J Urol 124:579–582
Breslow N, McCann B (1971) Statistical estimation of prognosis for children with neuroblastoma. Cancer Res 31:2098–2103
Finklestein JZ, Leikin S, Evans A (1975) Aggressive chemotherapy for stage 4 neuroblastoma (abstract). Pediat Res 9:386
Holland T, Donohue JP, Baehner RL, Grosfeld JL (1980) The current management of neuroblastoma. J Urol 124:579–582
Huges M, Marsden HB, Palmer MK (1974) Histologic patterns of neuroblastoma related to prognosis and clinical staging. Cancer 34:1706–1711
Graham PJ, Salmi T, Anton AN, Abramowsky C, Gross S (1983) Tumor and catecholamines (CATs) in neurogenic tumors. Cancer 51:834–839
Pahlman S, Esscher T, Bergh J, Steinholtz L, Nou E, Nilsson K (1984) Neuron-Specific enolase as a marker for neuroblastoma and small-cell carcinoma of the lung. Tumor Biol 5:119–126
Miller TR, Bottles K, Abele JS, Beckstead JH (1985) Neuroblastoma diagnosed by fine needle aspiration biopsy. Acta Cytol 29:461–468
Lane RH, Stephens DH, Reiman HM (1989) Primary retroperitoneal neoplasms: CT findings in 90 cases with clinical and pathologic correlation. Am J Rent 152:83–89
Hericak H, Demas BE, Williams RD, NcNamara MT, Hedgcock MW, Amparo E, Tanagho EA (1985) Magnetic resonance imaging in the diagnosis and staging of renal and perirenal neoplasms. Radiology 154:709–711
Donegan WL (1983) Cancer and pregnancy. Cancer J Clin CA33:194–197
Mitchell MS, Capizzi RL (1988) Neoplastic diseases. In: Burrow GN, Ferris TF (eds) Medical complications during pregnancy. 3rd edition. WB Saunders, Philadelphia, pp 540–569
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Ohashi, K., Sawada, H., Kanaizumi, T. et al. Adult neuroblastoma in pregnancy: Report of a case. Surg Today 23, 742–746 (1993). https://doi.org/10.1007/BF00311716
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DOI: https://doi.org/10.1007/BF00311716