Abstract
A retrospective analysis was conducted on 36 patients who underwent surgery for childhood or juvenile thyroid cancers and who were regularly followed up during the course of 30 years. The biological properties and late prognosis of these patients were assessed, and the clinical and morphological characteristics of the tumors were examined. The distribution of the DNA content in the tumor cells was compared with that in adult tumor cells, and the results of cytogenetic tests performed on mothers operated on for thyroid tumors and their children are also discussed.
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Bengtsson A, Malmaeus J, Grimelius L, Johansson H, Pontén J, Rastad J, Akerström G (1984) Measurement of nuclear DNA content in thyroid diagnosis. World J Surg 8:481–486
Cohn K, Bäckdahl M, Forselund G, Auer G, Lundell G, Löwhagen T, Tallroth E, Willems JS, Zetterberg A, Granberg PO (1984) Prognostic value of nuclear DNA content in papillary thyroid carcinoma. World J Surg 8:474–480
Lukács G, Mikó T, Fábián E, Zs-Nagy I, Csáky G, Balázs Gy (1983) The validity of some morphologic methods in the diagnosis of thyroid malignancy. Acta Chir Scand 149:759–765
Oláh É, Balogh E, Boján F, Juhász F, Stenszky V, Farid NR (1990) Cytogenetics of papillary carcinoma of the thyroid. Cancer Genet Cytogenet 44:119–129
Balázs Gy, Lukács G, Csáky G, Boros P, Ilyés I (1991) Late prognosis of childhood and juvenile thyroid carcinomas. Progr Pediatr Surg 26:41–47
Jääskeläinen MK, Lamberg BA (1985) Differentiated thyroid carcinoma in children. In: Jaffiol C, Milhaud G (eds) Thyroid carcinoma, Elsevier, Amsterdam, pp 357–358
La Quaglia MP, Corbally MT, Heller G, Exelby PR, Brennan MF (1988) Recurrence and morbidity in differentiated thyroid carcinoma in children. Surgery 104:1149–1154
Schlumberger M, DeVathaire F, Travagli JP, Vassal G, Lemerle J, Parmentier C, Tubiana M (1987) Differentiated thyroid carcinoma in childhood: long-term follow-up of 72 patients. J Clin Endocrinol Metab 65:1088–1094
Nikiforov Y, Gnepp DR (1994) Pediatric thyroid cancer after the Chernobyl disaster. Pathomorphological study of 84 cases (1991–1992) from the Republic of Belarus. Surgery 74(2):748–766
Zurnadzhi IuN, Bogdanova TI, Tron'ko ND, Rybakov SI, Chernii IaM, Komissarenko IV, Bolshova EV, Oleinik VA, Epstein EV, Shakmatova VA (1993) Morphofunctional characteristics of malignant thyroid gland tumors in children from various regions of the Ukraine who have been victims of the Chernobyl nuclear power plant accident. Arkh Patol 55(5):55–60
Hall P (1992) Radiation-induced thyroid cancer. Med Oncol Tumor Pharmacother 9(4):183–189
Mizukami Y, Michigishi T, Nonomura A, Hashimoto T, Noguchi M, Matsubara F, Watanabe K (1992) Carcinoma of the thyroid at a young age — a review of 23 patients. Histopathology 20(1):63–66
Tallroth E, Bäckdahl E (1986) Thyroid carcinoma in children and adolescents. Cancer 58:2329–2332
Antonini P, Venust AM, Linares G, Gillou B, Berger R, Parmentier C (1989) A translocation /7:10//q35:q21/in a differentiated papillary carcinoma of the thyroid. Cancer Genet Cytogenet 41:139–144
bondeson L, Bentson A, Bondeson AG, Dahlenfors R, Grimelius L, Wedell B, Mark J (1989) Chromosome studies in thyroid neoplasias. Cancer 64:680–685
Donghi R, Sozzi G, Pierotti MA, Biunno I, Miozzo M, Fusco A, Grieco M, Santoro M, Vecchio G, Spurr NK (1989) The oncogene associated with human thyroid papillary carcinoma /PTC/ is assignated to chromosome 10q11–12 in the same region as multiple endocrine neoplasia type IIA /MEN IIA/. Oncogene 4:521–523
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Balázs, G., Lukács, G., Juhász, F. et al. Special features of childhood and juvenile thyroid carcinomas. Surg Today 26, 536–540 (1996). https://doi.org/10.1007/BF00311563
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DOI: https://doi.org/10.1007/BF00311563