Abstract
We report herein the case of a 79-year-old man with adenoid cystic carcinoma (ACC) of the esophagus. The tumor had a polypoid appearance and was covered by thin esophageal mucosa. As the biopsy specimens suggested a diagnosis of poorly differentiated adenocarcinoma, the patient underwent subtotal esophagectomy with reconstruction of the gastric tube via the posterior mediastinum. Histologically, the carcinoma contained basaloid cells, cribriform foci, and a certain amount of eosinophilic hyaline substance. Some of the basaloid cells were stained immunohistochemically for keratin, muscle actin, and S-100 protein, a pattern which was identical to the pattern of immunoreactivity of the myoepithelium. We reviewed 36 other cases of ACC of the esophagus reported in Japan, with special reference to the criteria for histological diagnosis.
Similar content being viewed by others
References
Sweeney EC, Cooney T (1980) Adenoid cystic carcinoma of the esophagus: A light and electron microscopic study. Cancer 45:1516–1525
Suzuki H, Nagayo T (1980) Primary tumors of the esophagus other than squamous cell carcinoma — Histologic classification and statistics in the surgical and autopsied materials in Japan. Intern Adv Surg Oncol 3:73–109
Takubo K, Mafune K, Tanaka Y, Miyama T, Fujita K (1991) Basaloid-squamous carcinoma of the esophagus with marked deposition of basement membrane substance. Acta Pathol Jpn 41:59–64
Japanese Society for Esophageal Diseases (1992) Guidelines for the clinical and pathologic studies on carcinoma of the esophagus, 8th edn (in Japanese). Kanehara, Tokyo
Shima I, Kakegawa T, Yamana H, Fujita H, Uhi T, Morimatsu M (1993) Clinicopathologic studies on esophageal carcinoma with basaloid features (in Japanese with English abstract). Nippon Kyobu Geka Gakkai Zasshi (J Jpn Assoc Thorac Surg) 41:2067–2074
Kinoshita F, Yoshinaka H, Imamura H, Morinaga T, Kusano T, Baba M, Fukumoto T, Shimazu H (1990) A case of esophageal adenoid cystic carcinoma (in Japanese). Rinsho Geka (J Clin Surg) 45:1919–1923
Matsumoto M, Nomiyama T, Nakae J, Nishikawa H (1993) Combination chemotherapy for a senile patient with adenoid cystic carcinoma of the esophagus. Jpn J Clin Oncol 23:258–262
Akiyama H, Yanagida T, Nakamura T, Sasaki K, Akao S, Ishikawa H (1992) A case of adenoid cystic carcinoma of the esophagus (in Japanese). Nippon Shokakibyo Gakkai Zasshi (Jpn J Gastroenterol) 89:786
Monma K, Iwasaki Y (1993) A case of adenoid cystic carcinoma of the esophagus (in Japanese). I to Cho (Stomach Intestine) 28:994–996
Chaya M, Tejima A, Inoue T, Sato M, Ishiguro S, Tateishi R, Tsuzuki T (1988) A case of adenoid cystic carcinoma of the esophagus (in Japanese). Nippon Acta Radiol 48:537
Tono H, Tanaka M, Saito H, Baba T, Munakata A, Yoshida Y, Kako N, Takashima K (1988) A case of combined tumor of adenoid cystic carcinoma and squamous cell carcinoma of the esophagus (in Japanese). Nippon Shokakibyo Gakkai Zasshi (Jpn J Gastroenterol) 85:761
Mafune K, Takubo K, Tanaka Y, Fujita K (1986) Primary adenoid cystic carcinoma of the esophagus (in Japanese with English abstract). Gan no Rinsho (Jpn J Cancer Clin) 32:513–519
Tsang WYW, Chan JKC, Lee KC, Leung AKF, Fu YT (1991) Basaloid-squamous carcinoma of the upper aerodigestive tract and so-called adenoid cystic carcinoma of the oesophagus: the same tumor type? Histopathology 19:35–46
Morisaki Y, Shima S, Yoshizumi Y, Sugiura Y, Tanaka S (1993) Immunohistochemical study of basaloid-squamous carcinoma and adenoid cystic carcinoma of the esophagus (in Japanese with English abstract). J Jpn Res Soc Gastroenterol Carcin 5:171–173
Morisaki Y, Shima S, Yonekawa H, Yoshizumi Y, Sugiura Y, Otsuka H, Goto M, Tsuchiya C, Tanaka S, Ogata T, Ishii Y (1988) Esophageal carcinoma with an adenoid cystic differentiation — An immunohistochemical study of two cases with special reference to their histological origin (in Japanese with English abstract). Gan no Rinsho (Jpn J Cancer Clin) 34:1710–1717
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Morisaki, Y., Yoshizumi, Y., Hiroyasu, S. et al. Adenoid cystic carcinoma of the esophagus: Report of a case and review of the Japanese literature. Surg Today 26, 1006–1009 (1996). https://doi.org/10.1007/BF00309962
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00309962