Abstract
Osteosarcoma does not often affect the bones of the skull, occurring preferentially in the appendicular skeleton. The patient's age at onset seems to be later when the tumor is in the skull than in other sites. CT and MRI are at present the best means of establishing the extent of the tumor. Surgical removal of the lesion combined with polychemotherapy is the basis of treatment. We report a case of osteosarcoma of the skull in a child and review relevant publications.
Similar content being viewed by others
References
Arthur RJ, Brunelle F (1988) Computerized tomography in the evaluation of expansile lesions arising from the skull vault in childhood. A report of 5 cases. Pediatr Radiol 18:294–301
Bacci G (1990) Sarcomi Øssei. In: Santoro A, Bonadonna G (eds) Terapia medica oncologica 1990. SES, Naples, pp 530–554
Benson JE, Goske M, Han JS, Brodekey JS, Yoon YS (1984) Primary osteogenic sarcoma of the calvaria. AJNR 5:810–813
Bricout JH, De Kersant-Gilly A, Menegalli-Bogelli D, Nombalais F, Lavenant F, Robert R (1983) Osteosarcome du crâne sur maladie de Paget. J Radiol 64:133–137
Burkhardt A (1987) Knochentumoren im Kiefer-und Gesichtsbereich. Fehlerquellen und Probleme bei der Diagnostik und Einordnung. Pathologe 8:9–19
Caron AS, Hajdu SI, Strong EW (1971) Osteogenic sarcoma of the facial and cranial bones. A review of forty-three cases. Am J Surg 122:719–725
Casentini L, Visonà A, Colombo F, Stracca Pansa V, Benedetti A (1985) Osteogenic sarcoma of the calvaria following radiotherapy for cerebellar astrocytoma: report of a case in childhood. Tumori 71:391–396
Challa VR, Crone KR, Ferree CR, Moody DM, Kelly DL Jr (1986) Chronic vermal herniation in a case of osteosarcoma of the occipital bone. Neurosurgery 18:180–185
Dahlin DC, Unni KK (1986) Bone tumors: general aspects and data on 8,542 cases, 4th edn. Thomas, Springfield, Ill, pp 269–321
Gertner R, Podoshin L, Fradis M (1983) Osteogenic sarcoma of the temporal bone. J Laryngol Otol 97:627–631
Goodman MA, McMaster JH (1976) Primary osteosarcoma of the skull. Clin Orthop 120:110–114
Harrison DFN (1984) Osseous and fibro-osseous conditions affecting the craniofacial bones. Ann Otol Rhinol Laryngol 93:199–203
Hinton CE, Turnbull AE, O'Donnell HD, Harvey L (1989) Parosteal osteosarcoma of the skull. Histopathology 14:322–323
Huvos AG (1991) Bone tumors: diagnosis, treatment and prognosis, 2nd edn. Saunders, Philadelphia, pp 85–252
Huvos AG, Butler A, Bretsky SS (1983) Osteogenic sarcoma associated with Paget's disease of bone. A clinicopathological study of 65 patients. Cancer 52:1489–1495
Huvos AG, Sundaresan N, Bretsky SS, Butler A (1985) Osteogenic sarcoma of the skull. A clinicopathologic study of 19 patients. Cancer 56:1214–1221
Huvos AG, Woodard HQ, Cahan WG, Higinbotham NL, Stewart FW, Butler A, Bretsky SS (1985) Postradiation osteogenic sarcoma of bone and soft tissue. Cancer 55:1244–1255
Kornreich L, Grunebaum M, Ziv N, Cohen Y (1988) Osteogenic sarcoma of the calvarium in children: CT manifestations. Neuroradiology 30:439–441
Lee YY, Van Tassel P, Nauert C, Raymond KA, Edeiken J (1988) Craniofacial osteosarcomas: plain film, CT, and MR findings in 46 cases. AJNR 9:379–385
Malawer MM, Link MP, Donaldson SS (1989) Sarcomas of bone. In: DeVita VT Jr, Hellman S, Rosenberg SA (eds) Cancer, Principles and practice of oncology. Lippincott, Philadelphia, pp 1418–1468
Manor RS, Svetliza E, Reichenthal E, Yassur Y, Shalit M, Ben-Sira I (1984) Ocular changes in invasive osteogenic sarcoma of the skull. Ann Ophthalmol 16:68–74
Mazziotta JC, Jordan SE, Lones M (1989) Seizures and hemiparesis in a young woman 24 years after treatment of astrocytoma. Clinical conference. West J Med 150:180–186
Mehta RC, Wilson MA, Perlman SB (1988) Osteosarcoma arising in Paget's disease of the calvarium. J Nucl Med 29:414–416
Nora FE, Unni KK, Pritchard DJ, Dahlin DC (1983) Osteosarcoma of extragnathic craniofacial bones. Mayo Clin Proc 58:268–272
Ootsuyama A, Tanooka H (1989) Induction of osteosarcomas in mouse lumbar vertebrae by repeated external irradiation. Cancer Res 49: 1562–1564
Pagani JJ, Bassett LW, Winter J, Gold RH, Brawer M (1979) Osteogenic sarcoma after retinoblastoma radiotherapy. AJR 133:699–702
Papsidero MJ, Baker SR (1982) Osteogenic sarcoma of the ethmoid sinus. Otolaryngol Head Neck Surg 90:510–512
Ratfisch D (1984) Primäres Osteosarkom der Schädelbasis mit Garcin-Syndrom. Psychiatr Neurol Med Psychol (Leipz) 36:210–214
Reichenthal E, Cohen ML, Manor RS, Marshak G, Matz S, Shalit MN (1981) Primary osteogenic sarcoma of the sellar region. Case report. J Neurosurg 55:299–302
Rosen G, Eilber FR, Eckardt J, Mirra J (1990) Osteogenic sarcoma. In: Haskell CM (ed) Cancer treatment, 3rd edn. Saunders, Philadelphia, pp 533–547
Santoro A, Bonadonna G (1990) Soft tissue and bone sarcomas. Cancer Chemother Biol Response Modif 11:544–554
Sataloff RT, Myers DL, Spiegel JR, Roberts BR, Telian S (1988) Total bone resection for osteogenic sarcoma. Ear Nose Throat J 67:627–634
Schmidt A, Kob D, Kosmehl H (1988) Zur Kenntnis strahlenbedinger Sarkome. Mitteilung über 2 Beobachtungen. Zentralbl Allg Pathol Anat 134:41–45
Shinonaga M, Gondo G, Fujitsu K, Kuwabara T (1985) Intracranial osteogenic sarcoma complicating Paget's disease of bone. Case report. Neurol Med Chir (Tokyo) 25:45–49
Sundaresan N, Huvos AG, Rosen G, Galicich JH (1985) Combined-modality treatment of osteogenic sarcoma of the skull. J Neurosurg 63:562–567
Sundaresan N, Rosen G, Huvos AG, Krol G (1986) Postradiation sarcoma involving the spine. Neurosurgery 18:721–724
Sundaresan N, Schmidek HH, Schiller AL, Rosenthal DI (1990) Tumors of the spine. Diagnosis and clinical management. Saunders, Philadelphia, pp 86–98, 128–145
Takonis WK (1988) Osteosarcoma in fibrous dysplasia. Skeletal Radiol 17:163–170
Tanaka S, Nishio S, Morioka T, Fukui M, Kitamura K, Hikita K (1989) Radiation-induced osteosarcoma of the sphenoid bone. Neurosurgery 25:640–643
Triebel HJ, Spielman RP, Maas R (1989) Unusually localized osteosarcoma. RÖFÖ 150:615–616
Vaquero J, Carrillo R, Leunda G, Cabezudo JM (1979) Primary osteogenic sarcoma of the skull. Acta Neurochir (Wien) 51:97–104
Vener J, Rice DH, Newman AN (1984) Osteosarcoma and chondrosarcoma of the head and neck. Laryngoscope 94:240–242
Wang YC, Shih CJ, Leu FJ, Tu YC (1981) Primary osteogenic sarcoma of the skull: case report. Neurosurgery 9:307–310
Young HA, Hardy DG, Ashleigh R (1983) Osteogenic sarcoma of the skull complicating Paget's disease: case report. Neurosurgery 12:454–457
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Salvati, M., Ciappetta, P., Capone, R. et al. Osteosarcoma of the skull in a child: case report and review of the literature. Child's Nerv Syst 9, 437–439 (1993). https://doi.org/10.1007/BF00306202
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00306202