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Osteosarcoma of the skull in a child: case report and review of the literature

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Abstract

Osteosarcoma does not often affect the bones of the skull, occurring preferentially in the appendicular skeleton. The patient's age at onset seems to be later when the tumor is in the skull than in other sites. CT and MRI are at present the best means of establishing the extent of the tumor. Surgical removal of the lesion combined with polychemotherapy is the basis of treatment. We report a case of osteosarcoma of the skull in a child and review relevant publications.

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References

  1. Arthur RJ, Brunelle F (1988) Computerized tomography in the evaluation of expansile lesions arising from the skull vault in childhood. A report of 5 cases. Pediatr Radiol 18:294–301

    Google Scholar 

  2. Bacci G (1990) Sarcomi Øssei. In: Santoro A, Bonadonna G (eds) Terapia medica oncologica 1990. SES, Naples, pp 530–554

    Google Scholar 

  3. Benson JE, Goske M, Han JS, Brodekey JS, Yoon YS (1984) Primary osteogenic sarcoma of the calvaria. AJNR 5:810–813

    Google Scholar 

  4. Bricout JH, De Kersant-Gilly A, Menegalli-Bogelli D, Nombalais F, Lavenant F, Robert R (1983) Osteosarcome du crâne sur maladie de Paget. J Radiol 64:133–137

    Google Scholar 

  5. Burkhardt A (1987) Knochentumoren im Kiefer-und Gesichtsbereich. Fehlerquellen und Probleme bei der Diagnostik und Einordnung. Pathologe 8:9–19

    Google Scholar 

  6. Caron AS, Hajdu SI, Strong EW (1971) Osteogenic sarcoma of the facial and cranial bones. A review of forty-three cases. Am J Surg 122:719–725

    Google Scholar 

  7. Casentini L, Visonà A, Colombo F, Stracca Pansa V, Benedetti A (1985) Osteogenic sarcoma of the calvaria following radiotherapy for cerebellar astrocytoma: report of a case in childhood. Tumori 71:391–396

    Google Scholar 

  8. Challa VR, Crone KR, Ferree CR, Moody DM, Kelly DL Jr (1986) Chronic vermal herniation in a case of osteosarcoma of the occipital bone. Neurosurgery 18:180–185

    Google Scholar 

  9. Dahlin DC, Unni KK (1986) Bone tumors: general aspects and data on 8,542 cases, 4th edn. Thomas, Springfield, Ill, pp 269–321

    Google Scholar 

  10. Gertner R, Podoshin L, Fradis M (1983) Osteogenic sarcoma of the temporal bone. J Laryngol Otol 97:627–631

    Google Scholar 

  11. Goodman MA, McMaster JH (1976) Primary osteosarcoma of the skull. Clin Orthop 120:110–114

    Google Scholar 

  12. Harrison DFN (1984) Osseous and fibro-osseous conditions affecting the craniofacial bones. Ann Otol Rhinol Laryngol 93:199–203

    Google Scholar 

  13. Hinton CE, Turnbull AE, O'Donnell HD, Harvey L (1989) Parosteal osteosarcoma of the skull. Histopathology 14:322–323

    Google Scholar 

  14. Huvos AG (1991) Bone tumors: diagnosis, treatment and prognosis, 2nd edn. Saunders, Philadelphia, pp 85–252

    Google Scholar 

  15. Huvos AG, Butler A, Bretsky SS (1983) Osteogenic sarcoma associated with Paget's disease of bone. A clinicopathological study of 65 patients. Cancer 52:1489–1495

    Google Scholar 

  16. Huvos AG, Sundaresan N, Bretsky SS, Butler A (1985) Osteogenic sarcoma of the skull. A clinicopathologic study of 19 patients. Cancer 56:1214–1221

    Google Scholar 

  17. Huvos AG, Woodard HQ, Cahan WG, Higinbotham NL, Stewart FW, Butler A, Bretsky SS (1985) Postradiation osteogenic sarcoma of bone and soft tissue. Cancer 55:1244–1255

    Google Scholar 

  18. Kornreich L, Grunebaum M, Ziv N, Cohen Y (1988) Osteogenic sarcoma of the calvarium in children: CT manifestations. Neuroradiology 30:439–441

    Google Scholar 

  19. Lee YY, Van Tassel P, Nauert C, Raymond KA, Edeiken J (1988) Craniofacial osteosarcomas: plain film, CT, and MR findings in 46 cases. AJNR 9:379–385

    Google Scholar 

  20. Malawer MM, Link MP, Donaldson SS (1989) Sarcomas of bone. In: DeVita VT Jr, Hellman S, Rosenberg SA (eds) Cancer, Principles and practice of oncology. Lippincott, Philadelphia, pp 1418–1468

    Google Scholar 

  21. Manor RS, Svetliza E, Reichenthal E, Yassur Y, Shalit M, Ben-Sira I (1984) Ocular changes in invasive osteogenic sarcoma of the skull. Ann Ophthalmol 16:68–74

    Google Scholar 

  22. Mazziotta JC, Jordan SE, Lones M (1989) Seizures and hemiparesis in a young woman 24 years after treatment of astrocytoma. Clinical conference. West J Med 150:180–186

    Google Scholar 

  23. Mehta RC, Wilson MA, Perlman SB (1988) Osteosarcoma arising in Paget's disease of the calvarium. J Nucl Med 29:414–416

    Google Scholar 

  24. Nora FE, Unni KK, Pritchard DJ, Dahlin DC (1983) Osteosarcoma of extragnathic craniofacial bones. Mayo Clin Proc 58:268–272

    Google Scholar 

  25. Ootsuyama A, Tanooka H (1989) Induction of osteosarcomas in mouse lumbar vertebrae by repeated external irradiation. Cancer Res 49: 1562–1564

    Google Scholar 

  26. Pagani JJ, Bassett LW, Winter J, Gold RH, Brawer M (1979) Osteogenic sarcoma after retinoblastoma radiotherapy. AJR 133:699–702

    Google Scholar 

  27. Papsidero MJ, Baker SR (1982) Osteogenic sarcoma of the ethmoid sinus. Otolaryngol Head Neck Surg 90:510–512

    Google Scholar 

  28. Ratfisch D (1984) Primäres Osteosarkom der Schädelbasis mit Garcin-Syndrom. Psychiatr Neurol Med Psychol (Leipz) 36:210–214

    Google Scholar 

  29. Reichenthal E, Cohen ML, Manor RS, Marshak G, Matz S, Shalit MN (1981) Primary osteogenic sarcoma of the sellar region. Case report. J Neurosurg 55:299–302

    Google Scholar 

  30. Rosen G, Eilber FR, Eckardt J, Mirra J (1990) Osteogenic sarcoma. In: Haskell CM (ed) Cancer treatment, 3rd edn. Saunders, Philadelphia, pp 533–547

    Google Scholar 

  31. Santoro A, Bonadonna G (1990) Soft tissue and bone sarcomas. Cancer Chemother Biol Response Modif 11:544–554

    Google Scholar 

  32. Sataloff RT, Myers DL, Spiegel JR, Roberts BR, Telian S (1988) Total bone resection for osteogenic sarcoma. Ear Nose Throat J 67:627–634

    Google Scholar 

  33. Schmidt A, Kob D, Kosmehl H (1988) Zur Kenntnis strahlenbedinger Sarkome. Mitteilung über 2 Beobachtungen. Zentralbl Allg Pathol Anat 134:41–45

    Google Scholar 

  34. Shinonaga M, Gondo G, Fujitsu K, Kuwabara T (1985) Intracranial osteogenic sarcoma complicating Paget's disease of bone. Case report. Neurol Med Chir (Tokyo) 25:45–49

    Google Scholar 

  35. Sundaresan N, Huvos AG, Rosen G, Galicich JH (1985) Combined-modality treatment of osteogenic sarcoma of the skull. J Neurosurg 63:562–567

    Google Scholar 

  36. Sundaresan N, Rosen G, Huvos AG, Krol G (1986) Postradiation sarcoma involving the spine. Neurosurgery 18:721–724

    Google Scholar 

  37. Sundaresan N, Schmidek HH, Schiller AL, Rosenthal DI (1990) Tumors of the spine. Diagnosis and clinical management. Saunders, Philadelphia, pp 86–98, 128–145

    Google Scholar 

  38. Takonis WK (1988) Osteosarcoma in fibrous dysplasia. Skeletal Radiol 17:163–170

    Google Scholar 

  39. Tanaka S, Nishio S, Morioka T, Fukui M, Kitamura K, Hikita K (1989) Radiation-induced osteosarcoma of the sphenoid bone. Neurosurgery 25:640–643

    Google Scholar 

  40. Triebel HJ, Spielman RP, Maas R (1989) Unusually localized osteosarcoma. RÖFÖ 150:615–616

    Google Scholar 

  41. Vaquero J, Carrillo R, Leunda G, Cabezudo JM (1979) Primary osteogenic sarcoma of the skull. Acta Neurochir (Wien) 51:97–104

    Google Scholar 

  42. Vener J, Rice DH, Newman AN (1984) Osteosarcoma and chondrosarcoma of the head and neck. Laryngoscope 94:240–242

    Google Scholar 

  43. Wang YC, Shih CJ, Leu FJ, Tu YC (1981) Primary osteogenic sarcoma of the skull: case report. Neurosurgery 9:307–310

    Google Scholar 

  44. Young HA, Hardy DG, Ashleigh R (1983) Osteogenic sarcoma of the skull complicating Paget's disease: case report. Neurosurgery 12:454–457

    Google Scholar 

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Salvati, M., Ciappetta, P., Capone, R. et al. Osteosarcoma of the skull in a child: case report and review of the literature. Child's Nerv Syst 9, 437–439 (1993). https://doi.org/10.1007/BF00306202

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