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A FORTRAN program for the calculation and analysis of two-locus linkage disequilibrium coefficients

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Summary

A FORTRAN program was written that calculates composite linkage disequilibrium coefficients from genotypic data. Chi-square tests determine whether coefficients calculated for allele and locus pairs are significantly greater than zero. A subroutine is provided that partitions the variance in linkage disequilibrium into within- and between-subpopulation components. Output obtained from analysis of allozyme data collected from natural subpopulations of the house fly (Musca domestica L.) are included to illustrate features of the program.

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Authors and Affiliations

  1. Department of Entomology, Iowa State University, 50011, Ames, IA, USA

    W. C. Black IV & E. S. Krafsur

Authors
  1. W. C. Black IV
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  2. E. S. Krafsur
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Communicated by A. Robertson

Journal Paper No. J-11345 of the Iowa Agriculture and Home Economics Experiment Station, Ames, Iowa. Project No. 2411

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Black, W.C., Krafsur, E.S. A FORTRAN program for the calculation and analysis of two-locus linkage disequilibrium coefficients. Theoret. Appl. Genetics 70, 491–496 (1985). https://doi.org/10.1007/BF00305981

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  • DOI: https://doi.org/10.1007/BF00305981

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