Abstract
Congenital spinal cord astrocytomas have only rarely been reported. We report two additional cases and a review of the literature on these infrequent tumors. The congenital cord astrocytomas can have obscure initial presentations, including fever and irritability, leading to delays in diagnosis. Magnetic resonance imaging is the diagnostic procedure of choice, allowing noninvasive delineation of the lesion. The congenital tumors are similar in location and pathology to astrocytomas of the cord in older children. As in older patients, initial treatment should include attempted surgical extirpation, delaying or avoiding radiation therapy with its attendant risks. Reported follow-ups of the congenital astrocytomas suggest they will behave in a fashion similar to spinal cord astrocytomas in older children.
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References
Barkovitch AJ (1990) Neoplasms of the spine. In: Barkovitch J (ed) Pediatric neuroimaging, contemporary neuroimaging, vol 1. Raven Press, New York, pp 273–292
Chun HC, Schmidt-Ullrich RK, Wolfson A, Tercilla OF, Sagerman RH, King GA (1990) External beam radiotherapy for primary spinal cord tumors. J Neurooncol 9:211–217
Citron N, Edgar MA, Sheehy J, Thomas DGT (1984) Intramedullary spinal cord tumors presenting as scoliosis. J Bone Joint Surg [Br] 66:513–517
Cooper PR (1989) Outcome after operative treatment of intramedullary spinal cord tumors in adults: intermediate and long term results in 51 patients. Neurosurgery 25:855–859
DiLorenzo N, Giuffre R, Fortuna A (1982) Primary spinal neoplasms in childhood: analysis of 1234 published cases (including 56 personal cases) by pathology, sex, age and site. Differences from the situation in adults. Neurochirurgia 25:153–164
Epstein F (1986) Spinal cord astrocytomas of childhood. In: Symon L (ed) Advances and technical standards in neurology. Springer, New York Berlin Heidelberg, pp 135–169
Farwell JR, Dohrmann GJ, Flannery JT (1977) Central nervous system tumors in children. Cancer 40:3123–3132
Fornari M, Pluchino F, Solero CL, Giombini B, Luccarelli G, Oliveri G, Lasio G (1988) Microsurgical treatment of intramedullary spinal cord tumors. Acta Neurochir (Wien) Suppl 43:3–8
Gutierrez FA, Oi S, McLone DG (1983) Intraspinal tumors in children: clinical review, surgical results and follow-up in 51 cases. Concepts Pediatr Neurosurg 4:291–305
Hardison HH, Packer RJ, Rorke LB, Schut L, Sutton LN, Bruce DA (1987) Outcome of children with primary intramedullary spinal cord tumors. Child's Nerv Syst 3:89–92
Kiwak KJ, Deray MJ, Shields WD (1983) Torticollis in three children with syringomyelia and spinal cord tumor. Neurology 33:946–948
Mauser HW, Dokkum TA (1981) Astrocytomas involving the whole spinal cord — two case reports. Clin Neurol Neurosurg 83:239–245
Parizel PM, Baleriaux D, Rodesch A, Segebarth C, Lalmand B, Christophe C, Lemort M, Haesendonck P, Niendorf HP, Flament-Durand J, Brotchi J (1989) Gd-DTPA-Enhanced MR imaging of spinal tumors. AJR 152:1087–1096
Raffel C, Edwards MSB (1990) Intraspinal tumors in children. In: Youmans J (ed) Neurological surgery, 3rd edn. Saunders, Philadelphia, pp 3574–3588
Reimer R, Onofrio B (1985) Astrocytomas of the spinal cord in children and adolescents. J Neurosurg 63:669–675
Sundaresan N, Gutierrez FA, Larsen MB (1978) Radiation myelopathy in children. Ann Neurol 4:47–50
Umemoto M, Azuma A, Ohshima S, Arai S, Itoh M (1990) Congenital astrocytoma in the cervical spinal cord. Am J Dis Child 144:744–746
Vles JSH, Grubben CPM, Ooy A van, Weil EHJ (1990) Holocord astrocytomas in childhood. Clin Neurol Neurosurg 92:361–364
Wisoff JH, Epstein F (1985) Intramedullary astrocytoma of childhood: results of operative management in 63 children. 14th Pediatric Section-American Association of Neurological Surgeons meeting, Atlanta
Yasui T, Hakuba A, Katsuyama J, Nishimura S (1988) Microsurgical removal of intramedullary spinal cord tumors: report of 22 cases. Acta Neurochir (Wien) Suppl 43:9–12
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Kaufman, B.A., Park, T.S. Congenital spinal cord astrocytomas. Child's Nerv Syst 8, 389–393 (1992). https://doi.org/10.1007/BF00304786
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DOI: https://doi.org/10.1007/BF00304786