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The value of tumor-associated tissue inflammatory reaction in primary superficial bladder cancer

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Summary

The data of 92 patients who entered the prospective study between 1980 and 1982 were evaluable. The prevalence of tumor-associated tissue inflammatory reaction according to the tumorparameters stage, grade, multiplicity, tumor-weight and concomittant urothelial changes in primary superficial transitional cell cancer was estimated. Using high power field on the microscope tumor-associated cells were classified as lymphocytes, plasma cells, mast cells and eosinophils by morphological criteria. Recurrence rate, tumor progression and survival rate were evaluated for the group with tumor-associated cell infiltration and compared with the data of the group without any tumor-associated inflammatory reaction. According to recurrence rate, progression rate and survival rate there was a tendency to better prognosis for tumors with associated inflammatory reaction but this could not be proven by statistical analyses.

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References

  1. Cohen SG (1974) The eosinophil and eosinophilia. N Engl J Med 290:457

    Google Scholar 

  2. Dalesio O, Schulman CC, Sylvester R, De Pauw M, Robinson M, Denis L, Smith P, Viggiano G, and Members of the European Organisation for Research on Treatment of Cancer, Genitourinary Tract Cancer Cooperative Group (1983) Prognostic factors in superficial bladder tumors. J Urol 129:730

    Google Scholar 

  3. Flamm J, Benesch A (1984) Peritumorale Infiltration mononukleärer Leukozyten und klnischer Verlauf beim Harnblasenkarzinom. Wien Klin Wochenschr 96:735

    Google Scholar 

  4. Kaplan EL, Meier P (1958) Nonparametric estimation from incomplete observations. J Am Stat Assoc 53:457

    Google Scholar 

  5. Lowe D, Fletcher CDM, Gower RL (1984) Tumour-associated eosinophilia in the bladder. J Clin Pathol 37:500

    Google Scholar 

  6. Lutzeyer W, Rübben H, Dahm M (1982) Prognostic parameters in superficial bladder cancer: an analysis of 315 cases. J Urol 127:250

    Google Scholar 

  7. Mostofi FK, Davis CJ Jr, Sesterhenn IA (1988) Pathology of tumors of the urinary tract. In: Skinner DG, Lieskovsky G (eds) Diagnosis and management of genitourinary cancer, chapt 7. Saunders, Philadelphia, p 85

    Google Scholar 

  8. Rübben H (1988) Chemoprophylaxe beim superfizialen Blasenkarzinom. Urologe [A] 27:152

    Google Scholar 

  9. Sarma KP (1970) The role of lymphoid reaction in bladder cancer. J Urol 104:843

    Google Scholar 

  10. Schubert GE (1984) Präinvasive Befunde des Harnblasenurothels. In: Bichler KH, Harzmann R (eds) Das Harnblasenkarzinom. Springer, Berlin Heidelberg New York, p 63

    Google Scholar 

  11. Schubert GE, Pavkovic M, Kirchhoff L (1981) Metaplastische und proliferative Prozesse der Blasenschleimhaut im höheren Lebensalter. Urologe [A] 20:196

    Google Scholar 

  12. Stöber U (1978) Der Eihfluß der Lymphozyteninfiltration in Tumorgewebe auf Zeitpunkt und Infiltrationstendenz von Blasenkarzinomrezidiven. Urologe [A] 17:296

    Google Scholar 

  13. Tiltman AJ (1978) Eosinophilic infiltrates in carcinoma of the urinary bladder unassociated with schistosomiasis. J Pathol 126:79

    Google Scholar 

  14. UICC: International Union Against Cancer (1978) TNM classification of malignant tumours, 3rd edn. International Union Against Cancer, Geneva

    Google Scholar 

  15. WHO: World Health Organisation (1973) International histological classification of tumours, no 10: histological typing of urinary bladder tumours. WHO, Geneva

    Google Scholar 

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Flamm, J. The value of tumor-associated tissue inflammatory reaction in primary superficial bladder cancer. Urol. Res. 18, 113–117 (1990). https://doi.org/10.1007/BF00302470

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