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Prophylaxis of infection-induced kidney stone formation

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Summary

Lowering supersaturation with respect to struvite and carbonate apatite is the most important prophylactic measure in patients with infection-induced kidney stone disease. This is best achieved by combining culture-specific antibiotics with urinary acidification. Urinary infection with non-urease-producing Escherichia coli, probably promoting struvite particle formation, must be eradicated. Possible measures for improving urothelial anti-adherence properties or reducing bacterial adherence are discussed.

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Authors and Affiliations

  1. Policlinic of Medicine, University of Berne, Berne, Switzerland

    B. Hess

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  1. B. Hess
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Hess, B. Prophylaxis of infection-induced kidney stone formation. Urol. Res. 18, S45–S48 (1990). https://doi.org/10.1007/BF00301528

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