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Distribution of GABA-immunoreactive neurons in the forebrain of the goldfish, Carassius auratus

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Summary

The distribution of gamma-aminobutyric acid (GABA) immunoreactivity was studied in the forebrain (tel-and diencephalon) of the goldfish by means of immunocytochemistry on Vibratome sections using antibodies against GABA. Positive perikarya were detected in the olfactory bulbs and in all divisions of the telencephalon, the highest density being found along the midline. In the diencephalon, GABA-containing cell bodies were found in the hypothalamus, in particular in the preoptic and tuberal regions. The inferior lobes, the nucleus recessus lateralis, and more laterodorsal regions, such as the nucleus glomerulosus and surrounding structures, also exhibited numerous GABA-positive perikarya. Cell bodies were also noted in the thalamus, in particular in the dorsomedial, dorsolateral and ventromedial nuclei. The relative density of immunoreactive fibers was evaluated for each brain nucleus and classified into five categories. This ubiquitous distribution indicates that, as in higher vertebrates, GABA most probably represents one of the major neurotransmitters in the brain of teleosts.

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Authors and Affiliations

  1. Laboratoire de Physiologie des Interactions Cellulaires, UA CNRS 339, Talence, France

    Maria-Grazia Martinoli, Pierrette Dubourg, André Calas & Olivier Kah

  2. Laboratoire de Neuroimmunologie, IBCN CNRS, Bordeaux, France

    Michel Geffard

Authors
  1. Maria-Grazia Martinoli
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  2. Pierrette Dubourg
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  3. Michel Geffard
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  4. André Calas
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  5. Olivier Kah
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Martinoli, MG., Dubourg, P., Geffard, M. et al. Distribution of GABA-immunoreactive neurons in the forebrain of the goldfish, Carassius auratus . Cell Tissue Res 260, 77–84 (1990). https://doi.org/10.1007/BF00297492

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  • DOI: https://doi.org/10.1007/BF00297492

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