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Cytogenetic effects of cigarette smoke condensates in vitro and in vivo

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Summary

Various cigarette smoke condensates (CSC) were analyzed with respect to the induction of sister-chromatid exchanges (SCE) in human lymphocytes in vitro. CSC from a reference cigarette, from three different tobaccos of the reference cigarette, and from a British cigarette induced similar SCE frequencies. CSC from the reference cigarette did not induce SCE in Chinese hamster bone marrow cells in vivo.

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Authors and Affiliations

  1. Institut für Genetik, Freie Universität Berlin, Arnimallee 5/7, D-1000, Berlin 33, Bundesrepublik Deutschland

    Stephan Madle & Günter Obe

  2. Institut für Arzneimittel, Bundesgesundheitsamt, Postfach 33 00 13, D-1000, Berlin 33, Bundesrepublik Deutschland

    Anke Korte

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  1. Stephan Madle
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  2. Anke Korte
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  3. Günter Obe
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Madle, S., Korte, A. & Obe, G. Cytogenetic effects of cigarette smoke condensates in vitro and in vivo. Hum Genet 59, 349–352 (1981). https://doi.org/10.1007/BF00295470

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  • DOI: https://doi.org/10.1007/BF00295470

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