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Localization of the spherocytosis gene to chromosome segment 8p11.22→8p21.1

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Summary

A case of hereditary spherocytosis (HS) is reported. Cytogenetic study revealed a de nove minute deletion of chromosome 8. The critical portion which affected the expression of the HS phenotype appeared to be localized to 8p11.22→8p21.1.

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Authors and Affiliations

  1. Department of Clinical Genetics, Institute of Human Genetics, 920-02, Uchinada, Ishikawa, Japan

    M. Kitatani, H. Chiyo & M. Ozaki

  2. Department of Pediatrics, Kanazawa Medical University, 920-02, Uchinada, Ishikawa, Japan

    S. Shike

  3. The Institute of Medical Science, The University of Tokyo, Shiroganedai 4-6-1, Minato-ku, 108, Tokyo, Japan

    S. Miwa

Authors
  1. M. Kitatani
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  2. H. Chiyo
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  3. M. Ozaki
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  4. S. Shike
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  5. S. Miwa
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Kitatani, M., Chiyo, H., Ozaki, M. et al. Localization of the spherocytosis gene to chromosome segment 8p11.22→8p21.1. Hum Genet 78, 94–95 (1988). https://doi.org/10.1007/BF00291244

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  • DOI: https://doi.org/10.1007/BF00291244

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