Skip to main content
SpringerLink
Log in

A scheme for characterising ASG banding and an illustration of its use in identifying complex chromosomal rearrangements in irradiated human skin

  • Published:
Chromosoma Aims and scope Submit manuscript

Abstract

An example is given which illustrates the capacity of the ASG banding technique for the solution of complex radiation-induced structural changes such as those found surviving in human skin cells after radiotherapy. — With the aid of a G-band numbering system developed for such analyses, a detailed comparison has been made of banding patterns obtained and published by other authors.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Bridges, C. B.: Salivary chromosome maps. J. Hered. 26, 60–64 (1935).

    Google Scholar 

  • Caspersson, T., Lomakka, G., Zech, L.: The 24 fluorescence patterns of the human metaphase chromosomes — distinguishing characters and variability. Hereditas (Lund) 67, 89–102 (1971).

    Google Scholar 

  • Caspersson, T., Zech, L., Modest, E. J., Foley, G. E., Wagh, U., Simonsson, E.: DNA-binding fluorochromes for the study of the organization of the metaphase nucleus. Exp. Cell Res. 58, 141–152 (1969).

    Google Scholar 

  • Denver Conference 1960: A proposed standard system of nomenclature of human mitotic chromosomes. Ann. hum. Genet. 24, 319–324 (1960).

    Google Scholar 

  • Drets, M. E., Shaw, M. W.: Specific banding patterns of human chromosomes. Proc. nat. Acad. Sci. (Wash.) 68, 2073–2077 (1971).

    Google Scholar 

  • Evans, H. J., Buckton, K. E., Sumner, A. T.: Cytological mapping of human chromosomes: Results obtained with quinacrine fluorescence and the aceticsaline-Giemsa techniques. Chromosoma (Berl.) 35, 310–325 (1971).

    Google Scholar 

  • Gagne, R., Tanguay, R., Laberge, C.: Differential staining patterns of heterochromatin in man. Nature (Lond.) New Biol. 232, 29–30 (1971).

    Google Scholar 

  • Lindsley, D. L., Grell, E. H.: Genetic variations of Drosophila melanogaster. Carnegie Inst. Wash. Publ. 627 (1967).

  • Seabright, M.: A rapid banding technique for human chromosomes. Lancet 1971 II, 971–972.

    Google Scholar 

  • Seabright, M.: The use of proteolytic enzyme for the mapping of structural rearrangements in the chromosomes of man. Chromosoma (Berl.) 36, 204–210 (1972).

    Google Scholar 

  • Schnedl, W.: Analysis of the human karyotype using a reassociation technique. Chromosoma (Berl.) 34, 448–454 (1971).

    Google Scholar 

  • Shiraishi, Y., Yosida, T. H.: Banding pattern analysis of human chromosomes by use of urea treatment technique. Chromosoma (Berl.) 37, 75–83 (1972).

    Google Scholar 

  • Sumner, A. T., Evans, H. J., Buckland, R. A.: New technique for distinguishing between human chromosomes. Nature (Lond.) New Biol. 232, 31–32 (1971).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. M. R. C. Radiobiology Unit, Harwell, Berkshire, England

    T. R. L. Bigger, J. R. K. Savage & G. E. Watson

Authors
  1. T. R. L. Bigger
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. J. R. K. Savage
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. G. E. Watson
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bigger, T.R.L., Savage, J.R.K. & Watson, G.E. A scheme for characterising ASG banding and an illustration of its use in identifying complex chromosomal rearrangements in irradiated human skin. Chromosoma 39, 297–309 (1972). https://doi.org/10.1007/BF00290789

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00290789

Keywords

Search

Navigation