Summary
Q-and C-band heteromorphisms were determined by sequentially staining cells from 81 members of an American Black kindred. The incidence of heteromorphs is reported for 14-people who married into the family.
Small pericentric inversions of chromosome 3 were found in 23 kindred members, three of whom were homozygous. Six ‘complete’ chromosome 9 inversions and a single ‘partial’ inv9 were detected. There was no apparent phenotypic effect associated with the inversions, nor were duplication-deficiency chromosomes observed.
Evidence for preferential segregation of Q-heteromorphs is reported, and comparison with data from other authors points to chromosome 13 as showing the most distortion.
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Fogle, T.A., McKenzie, W.H. Cytogenetic study of a large black kindred: Inversions, heteromorphisms, and segregation analysis. Hum Genet 55, 345–352 (1980). https://doi.org/10.1007/BF00290216
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DOI: https://doi.org/10.1007/BF00290216