Abstract
The D and G group chromosomes from cultured human lymphocytes exhibit single and multiple satellite associations when stained with silver. Unlike earlier methods this simple and highly repeatable procedure shows physical attachments between satellited regions of various acrocentric autosomes. After studying 1,000 satellite associations from 118 normal individuals, it was found that both single and multiple associations occur with frequencies that correlate with random expectancies.
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Baserga, R.: Non-Histone chromosomal proteins in normal and abnormal growth. Life Sci. 15, 1057–1071 (1974)
Comings, D. E.: Biochemical mechanisms of chromosome banding and color banding with acridine orange. In: Chromosome identification-technique and applications in biology and medicine (T. Caspersson and L. Zech, eds.), Nobel Symp. 23, 293–299. New York: Academic Press 1973
Cooke, P.: Non random participation of chromosomes 13, 14, and 15 in acrocentric associations. Humangenetik 13, 309–314 (1971)
Cooke, P.: Age-Related variation in the number of secondary associations between acrocentric chromosomes in normal females and patients with Turner's Syndrome. Humangenetik 17, 29–35 (1972)
Curtis, D. J.: Acrocentric associations in mongol populations. Humangenetik 22, 17–22 (1974)
DeCapoa, A., Rocchi, A., Gigliani, F.: Frequency of satellite associations in individuals with structural abnormalities of nucleolus organiser region. Humangenetik 18, 111–115 (1973)
Eiberg, H.: Satellite staining of human chromosomes. Lancet 1974 II, 836–837
Faust, J., Vogel, W.: Are “N bands” selective staining of specific heterochromatin? Nature (Lond.) 249, 352–353 (1974)
Ferguson-Smith, M. A., Handmaker, S. D.: Observations on the satellited human chromosomes. Lancet 1961 I, 638–640
Howell, W. M., Denton, T. E., Diamond, J. R.: Differential staining of the satellite regions of human acrocentric chromosomes. Experientia (Basel) 31, 260–262 (1975)
Matsui, S., Sasaki, M.: Differential staining of nucleolus organizers in mammalian chromosomes. Nature (Lond.) 246, 148–150 (1973)
Nakagome, Y.: G-group chromosomes in satellite associations. Cytogenet. Cell Genet. 12, 336–341 (1973)
Rosenkranz, W., Holzer, S.: Satellite association. A possible cause of chromosome aberrations. Humangenetik 16, 147–150 (1972)
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Denton, T.E., Howell, W.M. & Barrett, J.V. Human nucleolar organizer chromosomes: satellite associations. Chromosoma 55, 81–84 (1976). https://doi.org/10.1007/BF00288330
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DOI: https://doi.org/10.1007/BF00288330