Summary
Chromosome studies were performed on 106 men with azoospermia and 390 men with oligozoospermia (consistant sperm count below 10 million/ml). Constitutional chromosome abnormalities were found in 14.1% of the azoospermia group and in 5.1% of the oligozoospermia group. An overall incidence of 7.1% constitutional abnormalities indicates that this criterion of selection may be advisable for routine chromosome analysis of infertile men. A reduction of 25% in the workload increases the yield of chromosome abnormalities in the group of infertile men to 10–14 times above that expected in the normal population.
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Retief, A.E., Van Zyl, J.A., Menkveld, R. et al. Chromosome studies in 496 infertile males with a sperm count below 10 million/ml. Hum Genet 66, 162–164 (1984). https://doi.org/10.1007/BF00286592
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DOI: https://doi.org/10.1007/BF00286592