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Das Plattenepithelcarcinom der Prostata als Beispiel einer Tumormetaplasie

The squamous-cell carcinoma of the prostate as an example of metaplasia in a tumor

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Summary

Squamous carcinoma represents an uncommon type of prostatic carcinoma. The etiology remains open to question till now. A squamous carcinoma developing during 20 months from a typical adenoid and cribriform carcinoma of the prostate is reported. The bulk of the carcinoma and the wide spread osseous metastases were of epidermoidal differentiation. Regressively changed tumor glands of the primary carcinoma were sparsely to be seen. Thus the described case is a case of tumor-metaplasia. In the duration of the disease an antiandrogenic therapy had been practized all the time. It seems to be unlikely that the hormonal therapy caused the metaplasia of the tumor.

Zusammenfassung

Das Plattenepithelcarcinom ist eine in der Prostata ungewöhnliche Tumorform. Die formale Genese ist bisher nicht hinreichend geklärt. Es wird ein verhornendes Plattenepithelcarcinom beschrieben, das sich innerhalb von 20 Monaten aus einem typischen, adenoid und cribriform differenzierten Prostatacarcinom entwickelte. Die Hauptmasse des Tumors sowie die ausgedehnten Skeletmetastasen waren epidermoid aufgebaut. Regressiv veränderte Tumordrüsen fanden sich vereinzelt. Bei dem dargestellten Fall handelt es sich somit um eine Tumormetaplasie. Die während des gesamten Krankheitsverlaufes durchgeführte antiandrogene Therapie erscheint als Ursache der Tumorumwandlung nicht in Frage zu kommen.

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Kastendieck, H., Altenähr, E. Das Plattenepithelcarcinom der Prostata als Beispiel einer Tumormetaplasie. Z. Krebsforsch. 82, 335–340 (1974). https://doi.org/10.1007/BF00285568

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  • DOI: https://doi.org/10.1007/BF00285568

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