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Arrangement of centromeres in mouse cells

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Abstract

Applying a staining procedure which reveals constitutive heterochromatin to cytological preparations of the mouse (Mus musculus), one detects heterochromatin pieces at the centromeric areas of all chromosomes except the Y. The Y chromosome is somewhat heteropyenotic in general but possesses no intensely stained centromeric heterochromatin. The arrangement of the centromeric heterochromatin in interphase cells is apparently specific for a given cell type. In meiotic prophase, centromeric heterochromatin may form clusters among bivalents. From the location of the centromeric heterochromatin of the X chromosome in the sex bivalent, it is concluded that the association between the X and Y (common end) in meiosis is limited to the distal portions of the sex elements.

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Authors and Affiliations

  1. Department of Biology, The University of Texas M. D. Anderson Hospital and Tumor Institute at Houston, Houston, Texas, USA

    T. C. Hsu, John E. K. Cooper, M. L. Mace Jr. & B. R. Brinkley

Authors
  1. T. C. Hsu
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  2. John E. K. Cooper
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  3. M. L. Mace Jr.
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  4. B. R. Brinkley
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Hsu, T.C., Cooper, J.E.K., Mace, M.L. et al. Arrangement of centromeres in mouse cells. Chromosoma 34, 73–87 (1971). https://doi.org/10.1007/BF00285517

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  • DOI: https://doi.org/10.1007/BF00285517

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