Summary
Glucose-6-phosphate dehydrogenase was tested in the blood of 305 males and 394 females, with Beutler's fluorescent spot test being used for screening. The percentage of deficiency was estimated at 12.4% for males and 8.8% for females of all ages; it was, however, highest among children and lowest among those over 50 years.
The efficiency of the fluorescent screening test in detecting heterozygote females was estimated at 35% and was derived by determining gene frequencies and comparing the expected and the observed.
References
Beutler E (1978) Haemolytic anaemia in disorders of red cell metabolism. Plenum Publishing Company, New York, pp 23–106
Dacie JV, Lewis SM (1975) Practical haematology. Churchill Livingstone, Edinburgh
De Grouchy GC (1975) Drug induced blood disorders. Blackwell, Oxford
Henry RJ, Cannon DC, Winkelman JW (1974) Clinical chemistry. Principles and Technics. Harper & Row, Hagerstown, Maryland. pp 849–853
Williams W, Beutler E, Erster A, Wayne R (1977) Haematology, 2nd edn. McGraw Hill, New York, pp 466–479
World Health Organization Report of Scientific Group (1972) Treatment of haemoglobinopathies and allied disorders. World Health Organisation: Technical Report Series, No 509. Who, Geneva
World Health Organization Report of Scientific Group (1973) Pharmacogenetics. World Health Organisation: Technical Report Series, No 524, pp 10–21
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Hamamy, H.A., Saeed, T.K. Glucose-6-phosphate dehydrogenase deficiency in Iraq. Hum Genet 58, 434–435 (1981). https://doi.org/10.1007/BF00282832
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DOI: https://doi.org/10.1007/BF00282832