Summary
Several regional series from Britain and 3 Asian series were typed for the Esterase D polymorphism. It was found that haemolysates up to 5 years old could be reliably typed when prepared from washed anticoagulated red blood cells. Lysates prepared from blood clots do not retain Esterase D activity quite as well. The Manx population has higher Esterase D 2 gene frequencies than neighbouring populations. A Nepalese population exhibits the highest Esterase D 2 gene frequency so far recorded. The other series presented supplement or confirm results already published.
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Bender, K., Frank, R.: Esterase D-Polymorphismus: Darstellung in der Hochspannungs-elektrophorese und Mitteilung von Allelhäufigkeiten. Humangenetik 23, 315–318 (1974)
Benkmann, H.-G., Goedde, H. W.: Esterase-D polymorphism: gene frequencies and family data. Humangenetik 24, 325–327 (1974)
Bethel, I. L.: Unpublished observation (1975)
Hopkinson, D. A., Mestriner, M. A., Cortner, J., Harris, H.: Esterase D: a new human polymorphism. Ann. hum. Genet. 37, 119–137 (1973)
Köster, B., Leupold, H., Mauff, G.: Esterase D polymorphism: high voltage agarose-gel electrophoresis and distribution of phenotypes in different European populations. Humangenetik 28, 75–78 (1975)
Mitchell, R. J.: Genetical variation in selected populations in the Isle of Man and neighbouring areas. Ph.D. thesis, Durham University (1974)
Parkin, B. H., Adams, E. G.: The typing of esterase D in human bloodstains. Med. Sci. Law 15, 102–105 (1975)
Welch, S. G., Lee, J.: The population distribution of genetic variants of human esterase D. Humangenetik 24, 329–331 (1974)
Wraxall, B. G. D., Culliford, B. J.: A thin layer starch gel method for enzyme typing of blood stains. J. forens. Sci. Soc. 8, 81–82 (1968)
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Cartwright, R.A., Bethel, I.L., Hargreaves, H. et al. The red blood cell Esterase D polymorphism in Europe and Asia. Hum Genet 33, 161–166 (1976). https://doi.org/10.1007/BF00281890
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DOI: https://doi.org/10.1007/BF00281890