Summary
Bile acids are steroids containing one — lithocholic acid, two — desoxycholic acid, and three — cholic acid hydroxyl groups, respectively. The hydroxyl group in position 3 of the steroid skeleton after esterification of the carboxyl group at C-24 under suitable conditions selectively reacts with methacryloyl chloride to give the corresponding methacrylic ester derivatives which undergo radically initiated uni- and copolymerizations to yield high molecular weight polymers.
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References
N.Ghediniand P.Ferruti, Synth.Commun. 13, 701 (1983)
N.Ghedini, P.Ferruti, V.Adrisano, and G.C.Scapini, Synth.Commun. 13, 707 (1983)
P.Ferruti, G.C.Scapini, L.Rusconi, and M.C.Tanzi, Polym. Sci. Technol. 23, 77 (1983)
H.Finkelmann, H.Ringsdorf, W.Siol, and J.H.Wendorff, Makromol. Chem. 179, 829 (1978)
L.F. Fieser and S. Rajagopalan, J. Am. Chem. Soc. 72, 5530 (1950)
NMR, Sadtler Research Laboratories, Division of Bio-Rad Laboratories, Inc. 40 122 M and 23 007 M
A.Satter and R.T.Blickenstaff, Steroids 17, 357 (1971) R.T.Blickenstaff, K.Atkinson, D.Breaux, E.Foster, Y.Kim, and G.C.Wolf, J. Org. Chem. 36, 1271 (1971) J.F.Baker and R.T.Blickenstaff, J. Org. Chem. 40, 1579 (1975)
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This paper is dedicated to Professor Georg Manecke on the occasion of his 70th birthday