Summary
Epidemiological data on Becker muscular dystrophy (BMD) and Duchenne muscular dystrophy (DMD) from a large sample of the Italian population are reported. For BMD the incidence rate was found to be 5.5x10-5 liveborn males (lbm) and the prevalence rate, 13.1x10-6; the mutation rate was estimated to be about 6.0x10-6. For DMD the incidence and prevalence rates were found to be respectively 26x10-5 lbm and 31.6x10-6. The DMD mutation rate obtained by the Haldane formula was 86.6x10-6 and by the semi-direct method, 65.6x10-6. The results are discussed in the light of possible allelism of BMD and DMD.
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Mostacciuolo, M.L., Lombardi, A., Cambissa, V. et al. Population data on benign and severe forms of X-linked muscular dystrophy. Hum Genet 75, 217–220 (1987). https://doi.org/10.1007/BF00281062
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DOI: https://doi.org/10.1007/BF00281062