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Chromosome studies in 2136 couples with spontaneous abortions

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Summary

Two thousand one hundred and thirty six couples with one or more spontaneous abortions (SAB) before 13 weeks of gestation and with or without one normal liveborn child (NLC) were karyotyped. In 4.31% of the couples one partner was a carrier of a major chromosomal abnormality. Couples with SAB only have 2-fold more chromosomal aberrations than couples with SAB and NLC. A correlation between the frequency of chromosomal abnormalities and the number of SAB was observed. Finally, the various types of chromosome aberrations were analysed.

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Authors and Affiliations

  1. Service de Génétique Médicale, Centre Régional de Transfusion Sanguine, CHU Purpan, F-31052, Toulouse Cedex, France

    G. Bourrouillou, P. Colombies & N. Dastugue

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  1. G. Bourrouillou
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  2. P. Colombies
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  3. N. Dastugue
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Bourrouillou, G., Colombies, P. & Dastugue, N. Chromosome studies in 2136 couples with spontaneous abortions. Hum Genet 74, 399–401 (1986). https://doi.org/10.1007/BF00280493

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  • DOI: https://doi.org/10.1007/BF00280493

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