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The effect of oxine and alloxan on the sulfide silver stainability of the rat brain

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Summary

Adult albino rats were injected intraperitoneally with oxine and alloxan in doses ranging from 100 to 400 mg per kg body weight. Two minutes to several hours following injection the animals were killed by vascular perfusion with buffered sodium sulfide and the brains immediately removed and frozen. Cryostat sections were prepared and stained according to Timm's procedure. A few animals were injected intracerebrally. In contrast to earlier reports by others it was found, under appropriate conditions, that oxine markedly reduced the staining of most parts of the neuropil of the forebrain while alloxan had no effect on the sulfide silver picture at all.

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Authors and Affiliations

  1. Institute of Anatomy, University of Aarhus, Denmark

    Gorm Danscher & Kjeld Fredens

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  1. Gorm Danscher
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  2. Kjeld Fredens
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Danscher, G., Fredens, K. The effect of oxine and alloxan on the sulfide silver stainability of the rat brain. Histochemie 30, 307–314 (1972). https://doi.org/10.1007/BF00279779

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  • DOI: https://doi.org/10.1007/BF00279779

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