Skip to main content
SpringerLink
Log in

Cross-reactions between human and animal plasma proteins

VI. An assay method for ape and monkey plasma proteins using antihuman antisera

  • Original Investigations
  • Published:
Humangenetik Aims and scope Submit manuscript

Summary

A quantitative assay for the estimation of several plasma proteins from subhuman primates by use of antihuman antisera is described. Both the Oudin and the Mancini method are suited for this purpose. Advantages and limitations of this new approach are shortly discussed. Several calibration curves are supplied.

Zusammenfassung

Es wird eine quantitative Bestimmungsmethode für einige Plasma-proteine von subhumanen Primaten beschrieben, bei welcher Antiseren gegen die jeweiligen menschlichen Homologen verwandt werden. Sowohl die Oudin- wie die Mancini-Technik sind anwendbar. Vorteile und Grenzen der neuen Methodik werden kurz besprochen. Einige Eichkurven werden als Beispiel angegeben.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Bauer, K.: Heterologe Reaktionen von Säugetierseren mit monospezifischen Antihumanseren. Ein Beitrag zur Evolution der Serumproteine. Humangenetik 7, 76–90 (1969)

    Google Scholar 

  • Bauer, K.: The antigenic determinants of several human plasma proteins. Their determination from the investigation of the cross-reactions between human and other mammalian plasmas. Int. J. Prot. Res. 2, 137–145 (1970a)

    Google Scholar 

  • Bauer, K.: An immunological time scale for primate evolution consistent with fossil evidence. Humangenetik 10, 344–350 (1970b)

    Google Scholar 

  • Bauer, K.: Die antigenen Determinanten der α- und μ-Ketten menschlicher Immunglobuline. Naturwissenschaften 57, 90 (1970c)

    Google Scholar 

  • Bauer, K.: Cross-reactions between human and animal plasma proteins. I. The immunological evolution groups (IEG) I and II. Humangenetik 8, 325–329 (1970d)

    Google Scholar 

  • Bauer, K.: Cross-reactions between human and animal plasma proteins. IV. Non-eutherian mammals. Humangenetik 13, 49–57 (1971)

    Google Scholar 

  • Bauer, K.: Cross-reactions between human and animal plasma proteins. V. The role of the antiserum and immunological specificity in relation to the phenomenon of cross-reaction. Humangenetik 21, 179–192 (1974)

    Google Scholar 

  • Buschmann, H., Schmid, D. O.: Serumgruppen bei Tieren. Berlin: Parey 1968

    Google Scholar 

  • Clausen, J.: Immunochemical techniques for the identification and estimation of macromolecules. Amsterdam-London: North-Holland 1969

    Google Scholar 

  • Goodman, M.: The specificity of proteins and the process of primate evolution. Protides of the biological fluids, p. 70. Amsterdam: Elsevier 1964

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Faculty of Theoretical Medicine, University of Heidelberg, Germany

    Klausdieter Bauer

Authors
  1. Klausdieter Bauer
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bauer, K. Cross-reactions between human and animal plasma proteins. Hum Genet 21, 273–278 (1974). https://doi.org/10.1007/BF00279022

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00279022

Keywords

Search

Navigation