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Résistance à l'ozone chez Escherichia coli

II. Relations avec certains mécanismes de réparation de l'ADN

Ozone resistance in Escherichia coli

II. Relations with some DNA repair mechanisms

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Summary

Different strains of E. coli commonly used in genetic studies were exposed to ozone and the results described in this paper indicate that exrA and (lex), but not uvrA genes affect sensitivity to ozone. No relationship between this latter property and the capacity to repair UV-damaged infecting phage (host cell reactivation) was also found. The hypothesis is proposed that the association of ozone sensitivity and X-rays sensitivity in the same mutants may reflect common steps in the mechanism of DNA repair.

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Bibliographie

  • Christensen, E., Giese, A. C.: Changes in adsorption spectra of nucleic acids and their derivatives following exposure to ozone and ultraviolet radiations. Arch. Biochem. Biophys. 51, 208–216 (1954)

    Google Scholar 

  • Chung, Y. S., Greenberg, J.: Genes affecting sensitivity to ultraviolet light in the malB region of the chromosome of Escherichia coli. Genetics 59, 11–22 (1968)

    Google Scholar 

  • Chung, Y. S., Hamelin, C.: The locus of the lex mutation in Escherichia coli (en préparation)

  • Davis, I.: Microbiologic studies with ozone: Mutagenesis of ozone for Escherichia coli. U.S.A.F. School of Aerospace Medicine Report No. SAM-TR-61-60, 1-9 (1961)

  • Fairchild, E. J., Murphy, S. D., Stokinger, H. E.: Protection by sulphur compounds against the air pollutants ozone and nitrogen dioxide. Science 130, 861–862 (1959)

    Google Scholar 

  • Fetner, R. H.: Chromosome breakage in Vicia faba by ozone. Nature (Lond.) 181, 504–505 (1958)

    Google Scholar 

  • Fetner, R. H.: Ozone-induced chromosome breakage in human cell cultures. Nature (Lond.) 194, 793–794 (1962)

    Google Scholar 

  • Giese, A. C., Christensen, E.: Effect of ozone on organisms. Physiol. Zool. 27, 101–115 (1954)

    Google Scholar 

  • Greenberg, J.: Loci for radiation sensitivity in Escherichia coli strain Bs-1. Genetics 55, 193–201 (1967)

    Google Scholar 

  • Hamelin, C., Chung, Y. S.: Résistance à l'ozone chez Escherichia coli: I. Etude comparative de différentes souches B et B/r. Rev. Canad. Biol. 32, 169–176 (1973)

    Google Scholar 

  • Howard-Flanders, P.: Molecular mechanisms in the repair of irradiated DNA. J. Genet. 40, 256–263 (1964)

    Google Scholar 

  • Howard-Flanders, P., Boyce, R. P.: DNA repair and genetic recombination: Studies on mutants of Escherichia coli defective in these processes. Radiat. Res., Suppl. 6, 156–184 (1966)

    Google Scholar 

  • Howard-Flanders, P., Boyce, R. P., Theriot, L.: Three loci in Escherichia coli K-12 that control the excision of pyrimidine dimers and certain other mutagen products from DNA. Genetics 53, 1119–1136 (1966)

    Google Scholar 

  • McGrath, R. A., Williams, R. W.: Reconstruction in vivo of irradiated Escherichia coli deoxyribonucleic acid; the rejoining of broken pieces. Nature (Lond.) 212, 534–535 (1966)

    Google Scholar 

  • Mount, D. W., Kosel, C.: Properties of strains of Escherichia coli K12 carrying mutant lex-1 and uvrA6 alleles. Molec. gen. Genet. 120, 291–299 (1973)

    Google Scholar 

  • Prat, R., Nofre, Cl., Cier, A.: Effets de l'hypochlorite de sodium, de l'ozone et des radiations ionisantes sur les constituants pyrimidiques de Escherichia coli. Ann. Inst. Pasteur. 114, 595–607 (1968)

    Google Scholar 

  • Sachsenmaier, W., Siebs, W., Tjong-An-Tan: Effects of ozone upon mouse ascites tumor cells and upon chick fibroblasts in tissue culture. Z. Krebsforsch. 67, 113–126 (1965)

    Google Scholar 

  • Scott, D. B., Lesher, E. C.: Effect of ozone on survival and permeability of Escherichia coli. J. Bact. 85, 567–576 (1963)

    Google Scholar 

  • Setlow, R. B., Carrier, W. L.: The disappearance of thymine dimers from DNA. An error correcting mechanism. Proc. nat. Acad. Sci. (Wash.) 51, 226–231 (1964)

    Google Scholar 

  • Wangermann, E., Lacey, H. J.: Some effects of ultraviolet radiation on Lemna minor. Nature (Lond.) 170, 126–127 (1942)

    Google Scholar 

  • Zelac, R. E., Cromroy, H. L., Bolch, W. E., Dunavant, B. G., Bevis, H. A.: Inhaled ozone as a mutagen: I. Chromosome aberrations induced in chinese hamster lymphocytes. Environ. Res. 4, 262–282 (1971a)

    Google Scholar 

  • Zelac, R. E., Cromroy, H. L., Bolch, W. E., Dunavant, B. G., Bevis, H. A.: Inhaled ozone as a mutagen: II. Effect on the frequency of chromosome aberrations observed in irradiated chinese hamster. Environ. Res. 4, 325–342 (1971b)

    Google Scholar 

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Authors and Affiliations

  1. Département des Sciences Biologiques, Faculté des Arts et des Sciences, Université de Montréal, Montréal, Québec, Canada

    Claude Hamelin & Young S. Chung

Authors
  1. Claude Hamelin
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  2. Young S. Chung
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Ce travail a pu être réalisé grâce à l'assistance financière du Conseil National de Recherches du Canada.

Boursier du Conseil National de Recherches du Canada.

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Hamelin, C., Chung, Y.S. Résistance à l'ozone chez Escherichia coli . Molec. Gen. Genet. 129, 177–184 (1974). https://doi.org/10.1007/BF00268630

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  • DOI: https://doi.org/10.1007/BF00268630

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