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Heterozygosity and segregation in Candida albicans

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Summary

Strain FC18 of the pathogenic yeast Candida albicans is heterozygous at a gene required for synthesis of methionine and cysteine, and yields auxotrophic derivatives by induced mitotic segregation. Derivatives of FC18 are heterozygous at other genes. Genetic analysis of C. albicans is feasible using induced mitotic recombination.

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Author notes

  1. William L. Whelan

    Present address: Dept. of Zoology Univ. of Iowa Iowa City, 52242, Iowa

Authors and Affiliations

  1. Department of Microbiology and Public Health, Michigan State University, 48824, East Lansing, Michigan, USA

    William L. Whelan, Roger M. Partridge & P. T. Magee

Authors
  1. William L. Whelan
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  2. Roger M. Partridge
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  3. P. T. Magee
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Additional information

Communicated by G. R. Fink

This is Article No. 9310 of the Michigan Agricultural Experiment Station

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Whelan, W.L., Partridge, R.M. & Magee, P.T. Heterozygosity and segregation in Candida albicans . Molec. Gen. Genet. 180, 107–113 (1980). https://doi.org/10.1007/BF00267358

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  • DOI: https://doi.org/10.1007/BF00267358

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