Skip to main content
Log in

Experimental study of the role of the motor endplate zone in the transplantation of skeletal muscle autografts in rabbits

  • Published:
Chirurgia plastica Aims and scope Submit manuscript

Summary

The vital role of the motor endplate zone in the survival of free autogenous skeletal muscle transplants, applied to orthotopic sites, was investigated in twelve rabbits. Such free grafts, when the muscle belly was divided into three segments, resulted in successful survival of the graft only in that segment containing the motor endplate zone.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Adams, R.D.: Diseases of muscle. A study in pathology. 3rd ed., Hagerstown, Maryland: Harper and Row 1975

    Google Scholar 

  2. Aitken, J.T.: Growth of nerve implants in voluntary muscle. J. Anat. 84, 38 (1950)

    Google Scholar 

  3. Barrett, B.: The length and mode of termination of individual muscle fibres in the human sartorius and posterior femoral muscles. Acta. Anat. 48, 242 (1962)

    Google Scholar 

  4. Coers, C., Woolf, A.L.: The innervation of muscle. A biopsy study, p. 14, Oxford: Blackwell 1959

    Google Scholar 

  5. Culling, C.F.A.: Handbook of histopathological technique. p. 316, London: Butterworth 1957

    Google Scholar 

  6. Ducker, T.B., Kempe, L.G., Hayes, G.J.: The metabolic background for peripheral nerve surgery. J. Neurosurg. 30, 270 (1969)

    Google Scholar 

  7. Erlacher, P.: Direct and muscular neurotization of paralysed muscles. Experimental research. Amer. J. Orthop. Surg. 13, 22 (1915)

    Google Scholar 

  8. Freilinger, G.: A new technique to correct facial paralysis. Plast. reconstr. Surg. 56, 44 (1975)

    Google Scholar 

  9. Freilinger, G., Holle, H., Mamoli, B.: Free muscle transplants for anal sphincter reconstruction in pigs. Chir. plastica (Berl.) 2, 133 (1974)

    Google Scholar 

  10. Gomori, G.: Microscopic histochemistry. p. 210, Chicago: University of Chicago Press 1952

    Google Scholar 

  11. Gruber, H., Freilinger, G., Holle, J., Mayr, R.: Motor endplates in autogenous muscle transplants. Experientia (Basel) 30, 1191 (1974)

    Google Scholar 

  12. Gutmann, E.: Factors affecting recovery of motor function after nerve lesions. J. Neurol. Psychiat. 5, 81 (1942)

    Google Scholar 

  13. Hakelius, L.: Transplantation of free autogenous muscle in the treatment of facial paralysis. A clinical study. Scand. J. plast. reconstr. Surg. 8, 220 (1974)

    Google Scholar 

  14. Hakelius, L., Nystrom, B.: Histochemical studies of endplate formation in free autologous muscle transplants in cats. Scand. J. plast. reconstr. Surg. 9, 9 (1975)

    Google Scholar 

  15. Hakelius, L., Nystrom, B., Stalberg, E.: Histochemical and neurophysiological studies of autotransplanted cat muscle. Scand. J. plast. reconstr. Surg. 9, 15 (1975)

    Google Scholar 

  16. Harreveld, A. van: On the force and size of motor units in the rabbit's sartorius muscle. Amer. J. Physiol. 151, 96 (1947)

    Google Scholar 

  17. Hogan, E.L., Dawson, D.M., Romanul, F.C.A.: Enzymatic changes in denervated muscle. II. Biochemical studies. Arch. Neurol. 13, 274 (1965)

    Google Scholar 

  18. Hogenhuis, L.A.H., Engel, W.K.: Histochemistry and cytochemistry of experimentally denervated guinea-pig muscle. I. Histochemistry. Acta Anat. 60, 39 (1965)

    Google Scholar 

  19. Holle, J., Freilinger, G., Gruber, H., Lischka, A., Mayr, R.: Tierexperimentelle Untersuchungen zur freien autologen Muskeltransplantation. Langenbecks Arch. Chir., Suppl. Chir. Forum 1974, 235

  20. Huber, G.C.: On the form and arrangement in fasciculi of striated voluntary muscle fibres. Anat. Rec. 11, 149 (1916)

    Google Scholar 

  21. Koelle, G.B.: The histochemical differentiation of types of cholinesterase and their localizations in tissues of the cat. J. Pharmacol. exp. Ther. 100, 158 (1950)

    Google Scholar 

  22. Lieberman, A.R.: The axon reaction. A review of the principal features of perikaryal responses to axon injury. Int. Rev. Neurobiol. 14, 49 (1971)

    Google Scholar 

  23. Lockhart, R.D., Brandt, W.: Length of striated muscle fibres. J. Anat. 72, 470 (1938)

    Google Scholar 

  24. McQuarrie, I.G., Grafstein, B.: Axon outgrowth enhanced by a previous nerve injury. Arch. Neurol. 29, 53 (1973)

    Google Scholar 

  25. Mazzola, R.F., Antonelli, A.R.: A contribution to the treatment of permanent facial paralysis by free muscle grafting based on 21 cases. Chir. plastica (Berl.) 3, 59 (1975)

    Google Scholar 

  26. Smith, B.: Changes in the enzyme histochemistry of skeletal muscle during experimental denervation and reinnervation. J. Neurol. Neurosurg. Psychiat. 28, 99 (1975)

    Google Scholar 

  27. Thompson, N.: Investigation of autogenous skeletal muscle free grafts in the dog. With a report of a successful free graft of skeletal muscle in man. Transplantation 12, 353 (1971)

    Google Scholar 

  28. Thompson, N.: A review of autogenous skeletal muscle grafts and their clinical applications. Clin. plast. Surg. 1, 349 (1974)

    Google Scholar 

  29. Thompson, N.: Free skeletal muscle autografts to the myocardium in dogs. A preliminary report. (Submitted for publication) 1978

  30. Zelena, J.: The effect of denervation on muscle development. In: The denervated muscle. Ed.: E. Gutmann, p. 103, Prague: Czechoslovakian Academy of Science 1962

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Thompson, N., Naftalin, A.P. & Lee, S.T. Experimental study of the role of the motor endplate zone in the transplantation of skeletal muscle autografts in rabbits. Chir Plastica 4, 81–85 (1978). https://doi.org/10.1007/BF00264540

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00264540

Key words

Navigation