Summary
Collagen/vicryl (Polyglactin) composite membrane has been used to repair full-thickness defects in the urinary bladder of rabbits. The material has been shown to be biodegradable, prevent leakage of urine, and is readily replaced by collagenous scar tissue lined with a urothelium. Regeneration of smooth nuscle has been observed in the repair area of some animals. The results suggest that such a material may well be of use to urologists wishing to augment contracted bladders or in the repair of bladder fistulae in human subjects, thereby avoiding the use of bowel or other material e.g. omentum.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Gorham SD, Monsour MJ, Scott R (1987) The in-vitro assessment of a collagen/vicryl (Polyglactin) composite film together with condidate suture materials for use in urinary tract surgery. I. Physical testing. Urol Res 15:53–59
Mohammed R, Monsour MJ, Gorham SD, French DA, Scott R (1987) The use of a biodegradable collagen/vicryl composite membrane to repair partial nephrectomy in rabbits. Urol Res 15:239–242
Tsuji I, Shiraishi Y, Kassai T, Kunishma K, Orikasa S, Abe N (1967) Further experimental investigations on bladder reconstruction without using the intestine. J Urol 97:1021
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Monsour, M.J., Mohammed, R., Gorham, S.D. et al. An assessment of a collagen/vicryl composite membrane to repair defects of the urinary bladder in rabbits. Urol. Res. 15, 235–238 (1987). https://doi.org/10.1007/BF00262106
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00262106