Abstract
The effect on the middle cerebral artery blood flow velocity (VMCA) of moderate and hard physical exercise on an ergometer cycle was examined in 10 healthy volunteers using transcranial Doppler sonography (TCD). During exercise, the heart rate increased by 136% and the systolic blood pressure by 37% (mean values). During initial moderate exercise, VMCA increased by 51%; in a following period of maximal physical work, VMCA decreased again by 20% in 9 of 10 volunteers although the heart rate continued to increase by 10% and the systolic blood pressure by 5% (mean values).
Constriction of the MCA may explain the initial increase of VMCA, suggesting a role for large cerebral arteries in autoregulation. Our data indicate that the subsequent decrease of VMCA is caused by arteriolar constriction, a likely cause of which was hyperventilation during the excessive work period.
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References
Aaslid R (ed): Transcranial Doppler sonography. Springer Verlag, Vienna/New York 1986
Aaslid R, K-F Lindegaard, W Sorteberg, H Nornes: Cerebral autoregulation dynamics in humans. Stroke 20 (1989) 45–52
Aaslid R, T-M Markwalder, H Nornes: Noninvasive transcranial Doppler ultrasound recording of flow velocity in basal cerebral arteries. J Neurosurg 57 (1982) 769–774
Briebach T, J Laubenberger, PA Fischer: Der Einfluß körperlicher Belastung auf die Flußgeschwindigkeit in der Arteria cerebri media. Eine transkraniell dopplersonographische Untersuchung. Ultraschall Med 10(5) (1989) 250–253
Edvinsson L, JE Hardebo, C Owman: Influence of the cerebrovascular sympathetic innervation on regional flow, autoregulation and blood brain barrier function. In: Cerebral Vascular Smooth Muscle and its Control. Ciba Foundation Symposium 56 (new series) (1977) 69–95
Ekström-Jodal B, E Häggendal, L-E Linder, NJ Nilsson: Cerebral blood flow autoregulation at high arterial pressures and different levels of carbon dioxide tensions in dogs. Eur Neurol 6 (1971) 6–10
Gosling RG, DH King: Continous wave ultrasound as an alternative or complement to X-rays in vascular examinations. In: Reneman (ed) Cardiovascular applications of ultrasound. North-Holland, Amsterdam 1974
Harper AM: Autoregulation of cerebral blood flow: influence of arterial pressure on blood flow through the cerebral cortex. J Neurol Neurosurg Psychiat 29 (1966) 398–403
Heistad DD, MI Marcus, FM Abboud: Role of large arteries in regulation of cerebral blood flow in dogs. J Clin Invest 62 (1978) 761–768
Hollman W, R Rost, K De Meirleir, H Liesen, H Heck, A Mader: Cardiovascular Effects of Extreme Physical Training. Acta Med Scand 19; Suppl 711 (1986) 193–203
Häggendal E, B Johansson: Effect of arterial carbon dioxide tension and oxygen saturation on cerebral blood flow autoregulation in dogs. Acta Physiol Scand Suppl 258 (1965) 27–53
Kontos HA: Validity of cerebral arterial blood flow calculations from velocity measurements (editorial). Stroke 20 (1989) 1–3
Sorteberg W, K-F Lindegaard, K Rootwelt, A Dahl, R Nyberg-Hansen, D Russell, H Nornes: Effect of Azetazolamide of the Cerebral Artery Blood Velocity and Regional Blood Flow in Normal Subjects. Acta Neurochir (Wien) 97 (1989) 139–145
Sperling B, N Lassen: Personal message
Strandgaard S, ET Mackenzie, D Sengupta, JO Rowan, NA Lassen, AM Harper: Upper limit of autoregulation of cerebral blood flow in the baboon. Circ Res 34 (1974) 435–440
Toole JF: Cerebrovascular disorders, 4th ed., Raven Press, New York 1990
Wahlgren NG, G Hellström, C Lindqvist, A Rudehill: Sympathetic nerve stimulation in man increases middle cerebral artery blood flow velocity. Cerebrovasc Dis 1992; 2: 359–364
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Hellström, G., Wahlgren, N.G. Physical exercise increases middle cerebral artery blood flow velocity. Neurosurg. Rev. 16, 151–156 (1993). https://doi.org/10.1007/BF00258249
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DOI: https://doi.org/10.1007/BF00258249