Abstract
To investigate the feasibility of radioiodinated free fatty acids for ‘metabolic imaging’, the kinetics and distribution pattern of metabolites of 131I-heptadecanoic acid were studied in canine myocardium throughout metabolic interventions. In control dogs and in dogs during glucose/insulin and sodium lactate infusion, biopsy specimens were taken during a 90-min period after 131I-HDA administration and analyzed. Clearly distinct patterns of distribution and elimination were seen during the metabolic interventions, indicating the usefulness of iodinated fatty acids for metabolic studies.
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Visser, F.C., van Eenige, M.J., Duwel, C.M.B. et al. Radioiodinated free fatty acids; can we measure myocardial metabolism?. Eur J Nucl Med 12 (Suppl 1), S20–S23 (1986). https://doi.org/10.1007/BF00258097
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DOI: https://doi.org/10.1007/BF00258097