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Preservation of the ischaemic canine kidney with inosine

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Summary

Direct intra-renal perfusion of inosine was found to protect the canine kidney from 90 min of warm is chaemia.

Significantly lower (P<0.01) serum creatinine levels were found 24 and 72 h post-operatively in an inosine treated group (N=12) when compared to a control group (N=5).

Histological examination of the pre-treated kidneys confirmed the protective effect of inosine.

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Authors and Affiliations

  1. Department of Surgery, Auckland University Medical School, Auckland, New Zealand

    D. Rothwell

  2. Department of Pathology, Auckland University Medical School, Auckland, New Zealand

    J. Bartley & M. James

Authors
  1. D. Rothwell
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  2. J. Bartley
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  3. M. James
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Rothwell, D., Bartley, J. & James, M. Preservation of the ischaemic canine kidney with inosine. Urol. Res. 9, 75–78 (1981). https://doi.org/10.1007/BF00256680

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  • DOI: https://doi.org/10.1007/BF00256680

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