Abstract
Factors influencing nitrogen balance during total parenteral nutrition have been investigated in 34 critically ill injured patients studied during the first 6 days after trauma. Basal nitrogen balance was severely negative (-0.26±0.12 (SD) g·kg-1), but improved consistently during treatment. Nitrogen intake proved to be the major determinant of a positive, or less negative, nitrogen balance, only secondarily followed by total energy intake corrected to predicted basal energy expenditure, according to multiple regression analysis. The amount of non-protein calories and the non-protein calorie to nitrogen ratio appeared to have little significance on nitrogen balance, when corrected for the two former variables.
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Iapichino, G., Radrizzani, D., Solca, M. et al. The main determinants of nitrogen balance during total parenteral nutrition in critically ill injured patients. Intensive Care Med 10, 251–254 (1984). https://doi.org/10.1007/BF00256262
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DOI: https://doi.org/10.1007/BF00256262