Abstract
A previously healthy 48-year-old male developed diabetic ketoacidosis and severe hypophosphatemia. Within a few hours, acute respiratory insufficiency developed with a marked discrepancy between the pulmonary pathology and the very poor oxygenation seen. We argue that this was due to the effect of hypophosphatemia on respiratory muscle- and heart function and P50, leading to impaired oxygen delivery.
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Agust AGN, Torres A, Estopa R, Agustividal A (1984) Hypophosphatemia as a cause of failed weaning: The importance of metabolic factors. Crit Care Med 12(2):142
Ditzel J (1973) Effect of plasma inorganic phosphate on tissue oxygenation during recovery from diabetic ketoacidosis. Adv Exp Med Biol 37A:163
Juan D, Elrazak MA (1978) Hypophosphatemia in hospitalized patients. J Am Med Assoc 242:163
Kingston M, Badawi Al-Siba' IM (1985) Treatment of severe hypophosphatemia. Crit Care Med 13(1):16
O'Connor LR, Wheeler WS, Bethune JE (1977) Effect of hypophosphatemia on myocardial performance in man. N Engl J Med 297:901
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Hasselstrøm, L., Wimberley, P.D. & Nielsen, V.G. Hypophosphatemia and acute respiratory failure in a diabetic patient. Intensive Care Med 12, 429–431 (1986). https://doi.org/10.1007/BF00254676
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DOI: https://doi.org/10.1007/BF00254676